TABLE 1.
Admission characteristics of the children in each group
| Characteristic | Group A | Group B | P value |
|---|---|---|---|
| n | 14 | 16 | |
| Age (mo), median (interquartile range) | 88 (72 to 109) | 85 (79 to 109) | 0.55 |
| Male sex, no. (%) | 8 (57) | 11 (69) | 0.71 |
| Duration of illness (days), mean (interquartile range) | 3 (2 to 4) | 3.5 (2 to 5) | 0.71 |
| Plasmodium falciparum density (per μl), median (interquartile range) | 22,905 (11,840 to 73,264) | 16,063 (950 to 33,255) | 0.35 |
| Body wt (kg), mean ± SD | 20 ± 4.3 | 19.3 ± 3.3 | 0.52 |
| Ht (cm), mean ± SD | 117 ± 12 | 116.2 ± 9.8 | 0.86 |
| Axillary temp (°C), mean ± SD | 37.5 ± 1.4 | 37.2 ± 1.1 | 0.47 |
| Mid-upper-arm circumference (cm), mean ± SD | 15.9 ± 1.6 | 15.7 ± 1.2 | 0.65 |
| Pulse rate (per min), median (interquartile range) | |||
| Supine | 92 (84 to 100) | 92 (83 to 109) | 0.76 |
| Standing | 96 (92 to 115) | 100 (100 to 120) | 0.048 |
| Blood pressure (mm Hg), median (interquartile range) | |||
| Supine systolic | 90 (75 to 100) | 90 (80 to 90) | 0.54 |
| Supine diastolic | 52 (45 to 60) | 50 (50 to 59) | 0.98 |
| Systolic change on standing | 0 (−8 to 4) | −10 (−10 to 3) | 0.30 |
| Diastolic change on standing | 0 (−5 to 2) | −3 (−10 to 0) | 0.055 |
| Respiratory rate (breaths per min), median (interquartile range) | 22 (20 to 28) | 23 (20 to 26) | 0.86 |
| Hemoglobin (g/liter), median (interquartile range) | 99.5 (77 to 108) | 105 (93 to 115) | 0.49 |
| Blood glucose (mmol/liter), median (interquartile range) | 6.6 (6.1 to 7.4) | 6.5 (6.0 to 6.9) | 0.44 |
| QTc (ms0.5), median (interquartile range) | 431 (421 to 440) | 430 (426 to 445) | 0.51 |