| ABVD-regimen: Adriamycine + Bleomycine + Vinblastine + Dacarbazine (Standard therapy) | |||||
| Diagn. | Mean age | # cases | Start trim. | Additional Drugs | Complication child (#w) |
|---|---|---|---|---|---|
| HL | NA | 32 | I | No | - Nihil |
| 6 | II | No | - 1 death due to prematuritas, Nihil | ||
| 4 | All Trim. | No | - 1 death in utero (32w), Nihil | ||
| M-/COPP-regimen: Mechlorethamine / Cyclophosphamide + Vincristine + Procarbazine + Prednisone | |||||
| HL | 25 | 22 | I | + cyclophosphamide | - IUGR, floating thumb, hypoplasie 2 phalanges (?w), other not specified malformations (?w), hydrocephalie, others: nihil |
| + ABVD | |||||
| 5 | II | No | - Nihil | ||
| 3 | All Trim. | No | - 1 Gastroenteritis (12w) + death, others were healty | ||
| Radiotherapy: mantleradiation, size and dose restricted, with shielding | |||||
| HL | NA | 17 | I | - abdominal shield | - Nihil |
| 26 | II | - measured fetal dose | - Nihil | ||
| 5 | III | - Nihil | |||
Hodgkin Disease – (Bachanova and Connors, 2008; Dilek et al., 2006; Ebert et al., 1997; Garcia et al., 1999; Wiebe and Sipila, 1994; Jones and Weinerman, 1975; Jacobs et al., 1981; Kal and Struikmans, 2005; Nuyttens et al. 2002).