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. 2014 Oct 7;8:315. doi: 10.3389/fncel.2014.00315

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Copyright © 2014 Xie, Choudhury, Wang, Park, Liu, Yuan, Zhang, Yorio, Jin and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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MB down-regulates cyclin expression in NPCs. (A) Detection of mRNA levels of cyclin (D,E,A,B) in NPCs at 24 h after MB treatment. (B) Western blot assay for cyclin expression in NPCs. This is a representative of three independent experiments. (C) Statistical analysis for cyclin protein levels. Expression level was normalized to each control group at 12 h after culture. N = 6 in each group. Ctrl, control; MB, MB-treated cells. *p < 0.05; **p < 0.01; ***p < 0.001 compared with control group.