Table 3.

Subcortical volumes of the PIVUS cohort, presented separately for men and women with Bonferroni-adjusted results of gender comparisons.

Regional subcortical volumes (mm3)	Females N = 193		Males N = 213		t-statistic	p-value Bonferroni adjusted
	Mean	Standard deviation	Mean	Standard deviation
Lateral ventricle	16108	7352	22240	10083	7.0	<0.0001
Inferior lateral ventricle	691	400	1032	522	7.4	<0.0001
Cerebellum WM	13060	1846	13603	2055	2.8	0.09*
Cerebellum cortex	45579	4262	49411	5116	8.2	<0.0001
Thalamus	5711	562	6216	579	8.9	<0.0001
Caudate	3210	485	3506	612	5.4	<0.0001
Putamen	4275	592	4587	590	5.3	<0.0001
Pallidum	1418	165	1545	166	7.7	<0.0001
Third ventricle	1628	511	2113	671	8.2	<0.0001
Fourth ventricle	1647	585	1922	633	4.5	<0.001
Brainstem	19169	2051	20931	2401	8.0	<0.0001
Hippocampus	3405	379	3515	384	2.9	0.07*
Amygdala	1241	167	1401	181	9.2	<0.0001
CSF	1348	416	1609	463	6.0	<0.0001
Accumbens	439	69	471	70	4.7	<0.0001
Ventral DC	3415	315	3738	366	9.5	<0.0001
Corpus callosum	2638	363	2779	411	3.7	<0.01

^*The unadjusted p-values are p = 0.004 for the cerebellum white matter and p = 0.005 for the hippocampus.