TABLE 1 ] .
Characteristics of Patients With IPF Used for Serum Analysis
| Characteristics | All IPF (N = 72) | Stable (n = 21) | Progressed (n = 27) | P Value |
| Mean (SD) | ||||
| Age, y | 68 (9) | 65 (11) | 70 (9) | nsa |
| FEV1, % predicted | 79 (20) | 79 (19) | 76 (20) | nsa |
| FVC, % predicted | 74 (20) | 78 (18) | 68 (21) | nsa |
| Dlco, % predicted | 41 (16) | 48 (18) | 33 (14) | .012a |
| CPI, units | 52 (13) | 44 (14) | 58 (10) | .002a |
| TLC, % predicted | 67 (13) | 75 (12) | 63 (12) | .027a |
| Serum fibulin-1, units | 2.04 (1.05) | 1.59 (0.83) | 2.34 (1.18) | .013a |
| No. (%) | ||||
| Male sex | 41 (57) | 10 (48) | 15 (56) | nsb |
| History of smoking | 45 (63) | 14 (74) | 19 (70) | nsb |
There were a total of 72 patients with IPF and of those 48 had follow-up information available. Continuous data of patients with IPF that either remained stable or progressed in the year following blood draw were compared by the Kruskal-Wallis test, and categorical data were compared with the Pearson χ2 test. CPI = composite physiologic index; Dlco = diffusing capacity of the lung for carbon monoxide; IPF = idiopathic pulmonary fibrosis; ns = nonsignificant; TLC = total lung capacity.
a
P value for Kruskal-Wallis test.
b
P value for Pearson χ2 test.