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Segmented dsRNA linear genome: 2 segments encode for a total of 3–4 proteins. Segments range in size from 1.7 to 2.5 kb. Total genome size is about 4.2 kb. Genomic organization of segments 1 and 2 of human picobirnavirus. The termination codon (UGA) for ORF1 and the initiation codon for (AUG) ORF2 in segment 1 are overlapped.
