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. 2014 Aug 25;86(19):9860–9865. doi: 10.1021/ac5024556

Table 2. Interaction Kinetic Constants between SB202190 and Different Proteins.

  Ka/M–1 s–1 Kd/s–1 KD/M
Abl1 6.4 × 101 3.5 × 10–3 1.6 × 10–5
Abl1 Y253F 5.7 × 101 1.8 × 10–3 3.2 × 10–5
p38-α 2.9 × 103 1.3 × 10–4 4.3 × 10–8