Table 2. Interaction Kinetic Constants between SB202190 and Different Proteins.
| Ka/M–1 s–1 | Kd/s–1 | KD/M | |
|---|---|---|---|
| Abl1 | 6.4 × 101 | 3.5 × 10–3 | 1.6 × 10–5 |
| Abl1 Y253F | 5.7 × 101 | 1.8 × 10–3 | 3.2 × 10–5 |
| p38-α | 2.9 × 103 | 1.3 × 10–4 | 4.3 × 10–8 |
| Ka/M–1 s–1 | Kd/s–1 | KD/M | |
|---|---|---|---|
| Abl1 | 6.4 × 101 | 3.5 × 10–3 | 1.6 × 10–5 |
| Abl1 Y253F | 5.7 × 101 | 1.8 × 10–3 | 3.2 × 10–5 |
| p38-α | 2.9 × 103 | 1.3 × 10–4 | 4.3 × 10–8 |