Figure 3.

(a), (g) 3 T in vivo endorectal T2-w prostate MR images ${\stackrel{‒}{\mathcal{C}}}^{T2}$ for two different patient studies (in each row), with manually placed bounding-boxes (in yellow) which serves as model initialization for MANTRA; (b), (h) resulting prostate boundary segmentations via MANTRA (in yellow). The WMHS ${\stackrel{‒}{\mathcal{C}}}^H$ corresponding to the MRI sections in (a), (g) with CaP extent outlined in blue by a pathologist are shown in (c) and (i), respectively. The result of registration of ${\stackrel{‒}{\mathcal{C}}}^H$ ((c), (i)) to ${\stackrel{‒}{\mathcal{C}}}^{T2}$ ((b), (h)) via COLLINARUS are sh ${\stackrel{‒}{\mathcal{C}}}^{T2}$ own in (d) and (j) respectively. Note the warped appearance of the WMHS in (d) and (j), which is now in spatial correspondence with ${\stackrel{‒}{\mathcal{C}}}^{T2}$ in (b) and (h) respectively. (e) and (k) show the mapping of the CaP extent (in green) from ${\mathcal{C}}^H$ onto ${\mathcal{C}}^{T2}$, following alignment to ${\mathcal{C}}^{T1,5}$ . (f) and (1) show the corresponding mapping of spatial CaP extent (in green) from the newly aligned ${\mathcal{C}}^H$ to ${\mathcal{C}}^{T1,5}$.