Table 3.
All-Cause Death/Hospitalization | CV Death/HF Hospitalization | All-Cause Death | CV Death | HF Hospitalization | |
---|---|---|---|---|---|
C-Statistics | |||||
Without CPX variables + age, race, NT-proBNP | 0.641 | 0.759 | 0.751 | 0.778 | 0.762 |
Without CPX variables + age, race, NT-proBNP + ST2 | 0.644 | 0.768 | 0.758 | 0.789 | 0.771 |
95% CI for Change in C-Statistic | (0.0003, 0.0048) | (0.0084, 0.0155) | (0.0043, 0.0125) | (0.0055, 0.0145) | (0.0079, 0.0149) |
IDI | 0.0002 | 0.0065 | 0.0078 | 0.0123 | 0.0043 |
95% CI for IDI | (−0.044, 0.0027) | (−0.0293, 0.0181) | (−0.0282, 0.0597) | (−0.0059, 0.0264) | (−0.0056, 0.0123) |
NRI | 0.025 | 0.015 | 0.049 | 0.0472 | 0.0638 |
95% CI for NRI | (−0.1142, 0.187) | (−0.2123, 0.2468) | (−0.2222, 0.1492) | (−0.3260, 0.1812) | (−0.0985, 0.2763) |
CI = confidence interval, CV = cardiovascular, IDI = integrated discrimination improvement, NRI = net reclassification improvement (without categories)