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. 2014 Sep 26;14:236. doi: 10.1186/s12866-014-0236-0

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© Britta et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Ultrathin sections of Leishmania amazonensis axenic amastigotes without treatment that presented a normal ultrastructure (A) and treated with BZTS with concentrations that corresponded to the IC ₅₀ (B-F) and IC ₉₀ (G,I). White arrows indicate swollen mitochondria. Black arrows represent lipid-storage bodies. White arrowheads indicate the presence of vesicles inside the flagellar pocket. The star indicates the presence of concentric membranous structures in the mitochondria. The asterisk indicates autophagic vacuoles. n, nucleus; m, mitochondrion; k, kinetoplast; f, flagellum; fp, flagellar pocket. Scale bar = 1 μm.