Table 1.

The genes with the top 10 most highly increased or decreased expression levels under submerged conditions when compared to A/L interface conditions at 24 h (A) or 48 h (B) after switching from culturing under A/L interface conditions. n=3 independent experiments.

A.
Gene Symbol	RefSeq	p-value (sub 24 hr vs. AL 24 hr)	Fold-Change (sub 24 hr vs. AL 24 hr)
Increased in Submerged at 24 h
Fam70b	NM_001106094	1.08E-11	75.0466
Th	NM_012740	3.88E-10	27.6918
Dock6	NM_001108997	4.73E-09	21.2716
Osap	NM_001109556	7.10E-08	14.3145
Stc1	NM_031123	9.23E-08	12.5598
Tmem213	ENSRNOT00000018331	9.69E-06	12.3558
Atp6v0a4	NM_001106591	3.46E-06	11.1214
Car9	NM_001107956	3.40E-06	10.7408
Hcrtr1	NM_013064	8.59E-11	9.60985
Eno2	NM_139325	1.24E-06	9.15644
Decreased in Submerged at 24 h
Lgi3	NM_001107277	1.96E-05	−7.87171
Aqp5	NM_012779	0.00285439	−7.08992
Angptl1	NM_001109383	1.27E-06	−6.77331
Retnla	NM_053333	1.47E-06	−6.01563
Kcne2	NM_133603	6.57E-05	−5.96204
Akr1c14	NM_138547	4.54E-05	−5.94269
Slc43a3	NM_001107743	0.00027989	−5.53856
Brms1l	NM_001106731	7.21E-07	−5.19932
Accn2	NM_024154	0.00033784	−4.89753
Akr1cl1	NM_001109900	0.00469004	−4.58958
B.
Gene Symbol	RefSeq	p-value (sub 48 hr vs. AL 48 hr)	Fold-Change (sub 48 hr vs. AL 48 hr)
Increased in Submerged at 48 h
Fam70b	NM_001106094	2.33E-10	33.8273
Th	NM_012740	1.06E-08	14.0543
Osap	NM_001109556	1.89E-07	11.883
Car9	NM_001107956	4.14E-06	10.3389
Stc1	NM_031123	3.41E-07	9.92379
Dock6	NM_001108997	2.93E-07	9.65169
Fxyd4	NM_022388	2.60E-06	9.30901
Ankrd34c	NM_001106845	1.98E-07	7.48247
Eno2	NM_139325	5.54E-06	7.10802
Mmp13	NM_133530	2.54E-06	6.94723
Decreased in Submerged at 48 h
Retnla	NM_053333	4.83E-11	−42.222
Lgi3	NM_001107277	1.83E-06	−12.4042
Slc43a3	NM_001107743	4.28E-06	−12.3659
Aqp5	NM_012779	0.000536135	−11.0382
Angptl1	NM_001109383	1.59E-07	−9.4264
Akr1c14	NM_138547	2.11E-05	−6.75691
Cyp2f4	NM_019303	0.00153741	−6.44771
Brms1l	NM_001106731	1.83E-07	−6.23451
Accn2	NM_024154	0.000104286	−5.99548
Pde7b	NM_080894	0.00452271	−5.21055