Table 5.
Multivariate analysis of prognostic factors
| Variable | Death |
Any event |
Relapse |
Death in CR |
||||
|---|---|---|---|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | |
| WBC at presentation | 1.004 (1.002-1.005) | < .001 | 1.003 (1.001-1.004) | < .001 | 1.004 (1.002-1.006) | .001 | NS | |
| Age | 1.02 (1.007-1.034) | .002 | 1.013 (1.000-1.025) | .04 | NS | 1.032 (1.005-1.061) | .02 | |
| Extra Ph chromosome [+der(22)] | NS | NS | 0.569 (0.342-0.946) | .03 | NS | |||
| del(9p) | NS | NS | 1.742 (1.036-2.928) | .04 | NS | |||
HR greater than 1 (unity) indicates increased risk of the event in relationship to the characteristic studied.
HR indicates hazard ratio; CI, confidence interval; and NS, not significant.