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. 2014 Oct 7;9(10):e109811. doi: 10.1371/journal.pone.0109811

Figure 5. Treatment with 17-N-Allylamino-17demethoxygeldanamycin (17-AAG) resulted in upregulation of CTGF and TGFβ2 mRNA, but not of YAP or TAZ in immortalized corneal epithelial cells.

Figure 5

The effect of HSP90 mediated regulation of CTGF and TGFβ2 were independent of topographic cues. The experiment was performed three times and at least 3 reactions were run for each sample. Results were expressed as mean ± standard deviation, n = 3 reactions. Statistical comparisons were performed using one-way ANOVA followed by Dunnett’s multiple comparison test; ***p<0.001 compared with DMSO control cells and ##p<0.01 compared with cells on planar surfaces.