Table 2. Group mean of digital analysis of immunohistochemical staining reveals increased apoptosis, proliferation, and acinar cell stress in areas of exenatide injury.

12 weeks treatment	TUNEL1	Ki-671	Reg3γ2
Saline	3.0±1.0	11.0±6.0	2227±1501
High dose exenatide	10.0±5.0*	50.0±10.0*	9858±2985*

1 = expressed in cells per millimeter squared; 2 = expressed in positive pixels per millimeter squared; * = significant at p<0.01; staining described in methods.