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. 2014 Oct 7;9(10):e109742. doi: 10.1371/journal.pone.0109742

Figure 1. Adipogenesis and secretion-related gene expression of mammary fat tissues.

Figure 1

(A) Representative images of H&E-stained sections of mammary fat from one patient with breast cancer (cancer associated fat, CAF) and from one with a benign lesion (negative control fat, NCF). Black arrows point to adipocytes (magnification100×). (B) Quantitative RT-PCR analysis of mRNA expression of adipogenesis-related genes: HOXC8, HOXC9, FABP4 and HSL (mean± SEM; n = 30; *P<0.05, **P<0.01). (C) Quantitative RT-PCR analysis of mRNA expression of secretion-related genes: TNFα, MCP-1, LEP and ADIPOQ (mean ± SEM; n = 30; *P<0.05, **P<0.01).