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. Author manuscript; available in PMC: 2015 Oct 15.
Published in final edited form as: Transplantation. 2014 Oct 15;98(7):721–728. doi: 10.1097/TP.0000000000000316

Figure 3. Activation of Nrf2 reduces hepatocellular apoptosis in liver IRI (6h of reperfusion after 90min of warm ischemia).

Figure 3

(A) Western-assisted analysis of cleaved caspase-3, Bcl-2/Bcl-xl. Representative of three experiments. (B/C) TUNEL staining. (a) WT; (b) WT+CoPP; (c) Nrf2 KO; (d) Nrf2 KO+CoPP; Mean±SD; Representative of 4 mice/group; magnification ×400 *p<0.005; **p<0.001.

Symbols used: sham ( Inline graphic ); WT ( Inline graphic ); WT+CoPP ( Inline graphic ); Nrf2 KO ( Inline graphic ); Nrf2 KO+CoPP ( Inline graphic ).