Skip to main content
. Author manuscript; available in PMC: 2014 Oct 15.
Published in final edited form as: Transplantation. 2014 Oct 15;98(7):766–772. doi: 10.1097/TP.0000000000000124

Figure 1. IGHV comparative repertoire analysis in blood and graft.

Figure 1

Pie chart representation of the frequency of clonotypic CDR3 sequences for each the 6 IGHV families (VH1-6) in the graft tissue (top row) and the peripheral blood (bottom row) of patient 2. Each pie chart section represents a distinct clonotypic CDR3. The size of each section corresponds to the frequency of the clonotypic sequences among all analyzed sequences. The number of clonotypic sequences observed is also indicated by a color code (left panel). The total number of sequences analyzed for each IGHV family is indicated below each pie. Pie sections filled in light or dark blue indicate clonotypic sequences found both in the patient blood and graft tissue. One clonotypic IGHV2 sequence highlighted in pink and indicated with an asterisk, corresponds to a polyreactive B cell clone expanded in the blood and further characterized in previous studies (29).