Table 3. Association between patient type and their physical, socio-demographic, microscopic and X-ray features among PTB patients in tertiary care hospitals of Kolkata, India, 2010–2013 (N = 350).
Patient type(ref: New infection) | ||||||||
Relapsed | Defaulter | Treatment failure | ||||||
Continuous Variables | OR(95%Cl) | p | OR(95%Cl) | p | OR(95%Cl) | p | ||
Body mass index (kg/m2) | UOR | 0.06(0.04–0.11) | <.001 | 0.44(0.30–0.66) | <.001 | <0.01(<0.01–0.01) | <.001 | |
AOR | 0.06(0.03–0.11) | <.001 | 0.45(0.28–0.74) | 0.002 | <0.01(<0.01–0.01) | <.001 | ||
Blood hemoglobin level (gm/dl) | UOR | 2.58(1.98–3.35) | <.001 | 3.33(2.32–4.79) | <.001 | 1.47(1.03–2.10) | 0.035 | |
AOR | 1.94(1.22–3.07) | 0.005 | 4.00(2.55–6.26) | <.001 | 0.67(0.29–1.57) | 0.354 | ||
Categorical variables | Relapsed | Defaulter | TF | |||||
Variables | Categories | OR(95%Cl) | p | OR(95%Cl) | p | OR(95%Cl) | p | |
Gender (ref: male) | Female | UOR | 0.71(0.41–1.24) | 0.228 | 1.27(0.63–2.53) | 0.503 | 1.40(0.61–3.19) | 0.423 |
AOR | 1.18(0.38–3.61) | 0.779 | 3.66(1.33–10.06) | 0.012 | 1.70(0.32–9.01) | 0.535 | ||
Age (ref:<20 yrs) | 20–45 yrs | UOR | 2.50(1.21–5.16) | 0.013 | 1.57(0.65–3.83) | 0.319 | 2.35(0.65–8.55) | 0.194 |
AOR | 10.44(1.6964.46) | 0.012 | 2.80(0.59–13.32) | 0.195 | 65.61(2.78–>99.99) | 0.010 | ||
>45 yrs | UOR | 3.56(1.37–9.24) | 0.009 | 1.20(0.32–4.47) | 0.788 | 3.83(0.81–18.09) | 0.090 | |
AOR | 8.95(1.05–76.41) | 0.045 | 1.76(0.25–12.71) | 0.574 | 77.02(1.90–>99.99) | 0.022 | ||
Marital status (ref: Married) | Unmarried | UOR | 0.33(0.18–0.60) | 0.001 | 0.40(0.17–0.89) | 0.026 | 0.55(0.22–1.40) | 0.210 |
AOR | 0.99(0.19–5.21) | 0.990 | 0.58(0.14–2.45) | 0.455 | 5.27(0.36–76.93) | 0.224 | ||
SES (ref: LIG) | MIG | UOR | 0.52(0.24–1.09) | 0.081 | 0.89(0.36–2.19) | 0.799 | 0.98(0.33–2.90) | 0.975 |
AOR | 0.46(0.13–1.72) | 0.251 | 0.69(0.23–2.10) | 0.515 | 1.57(0.19–12.99) | 0.678 | ||
HIG | UOR | – | – | – | – | – | – | |
AOR | – | – | – | – | – | – | ||
Resident of (ref: Kolkata) | North 24 Parganas | UOR | 0.23(0.05–1.19) | 0.079 | 1.35(0.36–5.03) | 0.656 | 0.54(0.06–4.66) | 0.573 |
AOR | 0.14(0.01–2.19) | 0.160 | 1.55(0.31–7.76) | 0.593 | 0.05(0.01–2.60) | 0.139 | ||
South 24 Parganas | UOR | 1.16(0.60–2.24) | 0.669 | 0.83(0.32–2.16) | 0.707 | 0.76(0.24–2.45) | 0.643 | |
AOR | 0.88(0.25–3.08) | 0.846 | 0.55(0.15–1.10) | 0.366 | 0.22(0.03–1.90) | 0.170 | ||
Sputum smear grading (ref: Single positive) | Double positive | UOR | 2.55(1.52–4.29) | 0.001 | 1.07(0.54–2.14) | 0.840 | 11.81(3.28–42.53) | 0.001 |
AOR | 1.48(0.47–4.73) | 0.505 | 1.01(0.35–2.90) | 0.988 | 2.23(0.25–19.85) | 0.472 | ||
Triple positive | UOR | 3.45(1.06–11.26) | 0.040 | 1.05(0.18–6.00) | 0.960 | 57.49(11.18–295.51) | <.001 | |
AOR | 0.84(0.07–10.56) | 0.892 | 1.05(0.06–17.33) | 0.971 | 0.92(0.03–32.08) | 0.963 | ||
X-ray (ref: Minimal) | Moderately advanced | UOR | 1.69(1.00–2.95) | 0.065 | 1.67(0.82–3.38) | 0.157 | 12.60(1.54–103.43) | 0.018 |
AOR | 1.15(0.38–3.49) | 0.806 | 1.99(0.78–5.07) | 0.152 | 1.64(0.11–24.83) | 0.722 | ||
Far advanced | UOR | 2.86(1.29–6.37) | 0.010 | 1.69(0.58–4.96) | 0.334 | 76.35(9.12–639.18) | <.001 | |
AOR | 1.95(0.32–11.91) | 0.468 | 1.66(0.30–9.24) | 0.563 | 9.77(0.44–217.99) | 0.150 | ||
Cavity | UOR | 8.17(2.29–29.07) | 0.001 | 0.89(0.09–9.03) | 0.921 | 130.65(1.91–>99.99) | <.001 | |
AOR | 4.54(0.41–50.66) | 0.220 | 0.55(0.02–13.24) | 0.713 | 33.93(0.84–>99.99) | 0.062 |
N = Total number of subjects in the study; SES = Socio-economic status; LIG = Low-income group; MIG = Middle-income group; HIG = High-income group; UOR = Unadjusted Odds ratio; AOR = Adjusted Odds ratio; OR = Odds ratio; CI = Confidence interval; p = p value.
“–” refers to cells for which due to inadequate number of observation valid statistical results (OR, CI, p value) could not be determined.