ligand	solubility (pH7, mmol/l)/logP	AC-/PLC- mediated Ca2+ response, EC50, μM	time of peak, s, AC-/PLC- dependent Ca2+ response	time to rise 10% to 90%, s, AC-/PLC- dependent Ca2+ response	decay time 90% to 10%, s, AC-/PLC- dependent Ca2+ response
eugenol	11/2.4	55±38/53.3±11	90.5±4.4/15.4±0.4	39.4±2.2/7.6±0.2	128.2±4.9/52.6±1.1
methyl eugenol	4.3/2.7	177±11/165.3±7.2	92±3/19.8±1.2	41.6±2.2/5.4±0.6	101.2±6/39.8±2.3
vanillin	28/1.2	162±68/ 218.1 ±27.1	85.3±2.9/18.6±0.9	31.4±1.3/8.3±0.5	101.7±2.6/48±2.9
ethyl vanillin	11/1.7	2165±131/1487±716	91.6±5.8/22.6±1.5	36.9±3.3/9.5±0.8	115.7±10.8/52.3±4.8
acetyl eugenol	1.4/2.7	373±49/348±25	90.8±3.4/19.6±0.9	27.6±1.7/7.7±0.4	125.5±5.1/44±1
orivone	2.4/3.1	4600±535/4370±471	94.9±5.3/29.8±2.3	36.4±2.6/8±1	101±5/47.6±4.1
methyl isoeugenol	3.6/3.05	non agonist, antagonist
isosafrole	0.6/3.9	non agonist, antagonist (*)
isoeugenol	7.3/3.08	286±40.3/35.4±4.8	95.3±4.8/37.1±3.5	36.7±2.7/14.8±1.6	104±4.8/54.5±2.6
4-propylguaiacol	6/2.9	205±15/174±88	95.8±3.9/23±1	46±3/5.7±0.4	128.2±8.5/36.3±2.8
4-ethylguaiacol	14/2.4	1057±861/66±44	79.3±2.3/22.1±0.8	31.5±1.7/6.1±0.3	101.6±6.7/71.3±4.9
4-vinylguaiacol	15/2.6	211±226/56.2±4.9	85.1±4.3/21.5±0.8	34.2±2.1/5.6±0.4	113±102/49.7±4.2
mousse cristal	10/2.8	551±22/253±81	107.3±2.4/30.7±1.4	32.6±1.6/14±1	117.6±5.3/74±4
nootkatone	0.24/3.8	no effects
raspberryketone	31/1.3	no effects
4-isopropylphenol	15/3	no effects
4-tert-butylphenol	6.3/3.4	no effects