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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Neuropharmacology. 2014 Aug 13;86:273–281. doi: 10.1016/j.neuropharm.2014.08.002

Figure 6.

Figure 6

A high concentration of ketamine does not reproduce the effects of low ketamine on EPSPs or LTP. A. Administration of 100 µM ketamine in the absence of synaptic stimulation for 30 min did not alter dendritic (circles) or somatic EPSPs (squares). HFS (100 Hz, 1s; arrow) delivered 75 min after washout of 100 µM ketamine induced LTP. B. HFS also induced LTP in slices pretreated with 100 µM ketamine × 30 min (circles) administered 2–4 hours before experiments. Traces show representative waveforms at designated times with the initial control traces as thin lines. Calibration: 1 mV, 5 msec.