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. 2014 Oct;184(10):2662–2670. doi: 10.1016/j.ajpath.2014.06.016

Figure 1.

Figure 1

Measurements of body weight and serum glucose level in STZ-treated mice. Body weight was reduced significantly in the STZ-treated group (light gray) compared with the vehicle-treated controls (dark gray) at 12 weeks (n = 6) (A) and at 18 weeks (n = 8) (B). There were no differences between the groups at baseline. Serum glucose level was increased significantly at 12 weeks (n = 6) (C) and at 18 weeks (n = 8) (D) in the STZ-treated groups compared with the vehicle-treated controls. There were no differences in serum glucose level at baseline in either group. Data are expressed as means ± SD. ∗∗∗P < 0.001, ∗∗∗∗P < 0.0001.