Table 2.

Association between major depressive disorder and Parkinson's disease and other clinical correlates

Variables	Total no (%)	Depression		OR (95% CI)	p value
		Yes	No
Age of PD onset (years)
<40	10(9.6%)	4(40.0%)	6(60.0%)	1	0.813
41-50	20(19.2%)	9(45.0%)	11(55.0%)	1.22(0.26-5.73)
51-60	42(40.4%)	13(31.0%)	29(69.0%)	0.67(0.16-2.79)
61-70	26(25.0%)	11(42.3%)	15(57.7%)	1.10(0.24-4.85)
>70	6(5.8%)	2(33.3%)	4(66.7%)	0.75(0.09-6.23)
Duration of PD (years)
< 5	42(40.4%)	28(66.7%)	14(33.3%)	1	0.114
5 to 10	28(26.9%)	13(46.4%)	15(53.6%)	2.30(0.86-6.15)
> 10	34(32.7%)	24(70.6%)	10(29.4%)	0.83(0.31-2.21)
Levodopa dose (mg/day)
< 250	15(14.4%)	4(26.7%)	11(73.3%)	1	0.8
250 - 500	41(39.4%)	16(39.0%)	25(61.0%)	1.76(0.47-6.49)
500 - 750	22(21.2%)	10(45.5%)	12(54.5%)	2.29(0.55-9.47)
750 - 1000	15(14.4%)	5(33.3%)	10(66.7%)	1.37(0.28-6.60)
1000 - 1250	9(8.7%)	4(44.4%)	5(55.6%)	2.20(0.38-12.57)
Ropinirole treatment
Yes	21(20.2%)	11(52.4%)	10(47.6%)	10(47.6%)	0.115
No	83(79.8%)	28(33.7%)	55(66.3%)	55(66.3%)
Diabetes
Yes	12(11.5%)	9(75.0%)	3(25.0%)	6.2(1.56-24.5)	0.004
No	92(88.5%)	30(32.6%)	62(67.4%)	1
Significant chronic medical illness comorbid with PD
Yes	48(46.2%)	22(45.8%)	26(54.2%)	1.96	0.086
No	56(53.8%)	17(30.4%)	39(69.6%)	1
Hoehn-Yahr stage
I and II	24(23.1%)	2(8.3%)	22(91.7%)	1	0.003
III	55(52.9%)	27(49.1%)	28(50.9%)	10.61(2.27-49.53)
IV and V	25(24.0%)	10(40.0%)	15(60.0%)	7.33(1.40-38.33)
Schwab-England score (%)
≥80	43(41.4%)	8(18.6%)	35(81.4%)	1	0.008
50-70	45(43.3%)	24(53.3%)	21(46.7%)	5.00(1.90-13.13)
30-40	12(11.5%)	5(41.7%)	7(58.3%)	3.12(0.78-12.43)
≤20	4(3.8%)	2(50.0%)	2(50.0%)	4.37(0.53-35.90)
Caregiver
Independent	25(24.0%)	5(20.0%)	20(80.0%)	1	0.038
Dependent	79(76.0%)	34(43.0%)	45(57.0%)	3.02(1.03-8.86)

OR – Odds ratio.