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. 2014 Oct 7;20(37):13246–13257. doi: 10.3748/wjg.v20.i37.13246

Table 3.

Clinical significance of proteolytic enzymes in colorectal cancer

Role in colorectal tumor biology, in the process of tumor invasion and metastasis
Role in malignant transformation of colorectal precancerous conditions and lesions
Potential diagnostic tool
New and independent prognostic factors
Potential tumor marker impact for early diagnosis
Potential target molecules for therapeutic agents