Table 1.
Therapeutic outcomes of endoscopic resection for early gastric cancer
| Ref. | Published year country | No. (lesion/patients) |
Method |
En bloc resection (%) |
Complete resection (%) |
Follow-up (mo/range) |
Complications |
Recurrence rate
(%) |
5-yr overall survival rate (%) | 5-yr recurrence-free rate (%) | |||||||||
|
Bleeding |
Perforation |
||||||||||||||||||
| EMR | ESD | EMR | ESD | EMR | ESD | EMR | ESD | EMR | ESD | Local | Metachronous | ||||||||
| Oda et al[15] | 2006 Japan | 714/655 | 411 | 303 | 56.0 | 66.3 | 61.1 | 73.6 | 38 (6-60) | 0.1 | 0 | 1.2 | 3.6 | 7.5 | NA | 99.21 | 94.42 | ||
| Oka et al[11] | 2006 Japan | 1020/896 | 825 | 195 | 42.1 | 83.1 | 23.6 | 83.1 | EMR 83.2 ± 34.6 ESD 19.4 ± 9.2 | 7.6 | 22.6 | 4.8 | 8.7 | 3.1 | NA | NA | NA | ||
| Imagawa et al[21] | 2006 Japan | 196/185 | 196 | 93.0 | 84.0 | 22.8 (12-46) | 6.1 | 0.0 | NA | NA | NA | ||||||||
| Chung et al[19] | 2009 Korea | 534/1000 (dysplasia 466) | 534 | 95.3 | 87.7 | NA | 15.6 | 1.2 | NA | NA | NA | NA | |||||||
| Jang et al[22] | 2009 Korea | 198/198 | 198 | 89.7 | 87.9 | 30 (9-49) | 7.4 | 2.9 | 5.1 | NA | NA | 94.92 | |||||||
| Min et al[24] | 2009 Korea | 346/243 | 103 | 243 | 77.7 | 95.9 | 75.7 | 88.9 | 29 (4-44) | 3.9 | 5.3 | 1.9 | 4.5 | 0.0 | 6 | NA | NA | ||
| Isomoto et al[25] | 2009 Japan | 589/551 | 589 | 94.9 | 94.7 | 30 (6-89) | 1.8 | 4.5 | 0.0 | NA | 97.1 | 1003 | |||||||
| Goto et al[20] | 2009 Japan | 276/231 | 276 | 96.7 | 91.7 | 36 (2-39) | 5.1 | 4.0 | 0.9 | NA | 96.2 | 1003 | |||||||
| Nakamoto et al[10] | 2009 Japan | 202/177 | 80 | 122 | 53.8 | 94.3 | 37.5 | 92.6 | 54 (12-89) | 0 | 1.6 | 2.5 | NA | 100.0 | 100 | ||||
| Choi et al[8] | 2011 Korea | 215/215 | 215 | 71.2 | 81 (56-94) | NA | NA | 93.6 | 98.7 | ||||||||||
| Ahn et al[17] | 2011 Korea | 1370/1244 | Absolute Ix | 32 (22-48) | 98.8-99.02 | ||||||||||||||
| 355 | 182 | 72.4 | 65.9 | 94.4 | 83.0 | 1.4 | 0.8 | 0.3 | 1.2 | 1.5 | 0.5 | 6.1 | 2.2 | 95.8-95.3 | |||||
| Expanded Ix | |||||||||||||||||||
| 497 | 336 | 96.8 | 95.5 | 97.8 | 91.1 | 1.6 | 2.1 | 1.6 | 2.4 | 1.6 | 0.8 | 13.7 | 4.0 | 96.8 | 98.52 | ||||
| Catalano et al[29] | 2009 Italy | 48/45 | 36 | 12 | 72.0 | 92.0 | 56.0 | 92.0 | 31 (12-71) | 8.0 | 8 | 0.0 | 8.0 | 0.0 | NA | NA | NA | ||
| Dinis-Ribeiro et al[30] | 2009 Portugal | 19/19 | 19 | 79.0 | 89.0 | 10 | 5 | 0.0 | 0.0 | NA | NA | NA | |||||||
| Probst et al[34] | 2010 Germany | 91/83 (EGC 66) | 1 | 85 | 100.0 | 88.2 | 90.0 | 68.6 | 27 (1-71) | 3.5 | 1.2 | 6.6 | NA | NA | 90.12 | ||||
| Schumacher et al[36] | 2012 Germany | 30/30 (EGC 21) | 30 | 90.0 | 64.3 | 22 | 4 | 6.0 | 10.7 | NA | NA | NA | |||||||
| Repici et al[35] | 2013 Italy | 42/42 (EGC 10) | 42 | 100.0 | 92.8 | 19 (9-53) | 7.1 | 0.0 | 5.0 | NA | NA | NA | |||||||
| Chaves et al[32] | 2013 Brazil | 62/61 (EGC 55) | 62 | 82.2 | 77.4 | 11.3 (1-30) | 0 | 4.8 | 0.0 | 3.5 | NA | NA | |||||||
1
3-year overall survival rate;
2
3-year recurrence free rate;
3
5-year disease specific survival. EGC: Early gastric cancer; EMR: Endoscopic mucosal resection; ESD: Endoscopic submucosal dissection; NA: Not applicable; Ix: Indication.