Table 2.

Detection of hepatitis B virus DNA regions, serologic markers, and ART treatment in 24 human immunodeficiency virus-1 patients identified with occult hepatitis B infection

Patient ID	HBV serological markers			qPCR1		C-nested PCR	RNA HIV (CV) Log10 c/mm3	HAART Tx	HBV Tx2
	αHBc	αHBs	αHBe	S	X
SP
HBVO-04	+	-	-	+	+	+	3.1	+	-
HBVO-05	+	-	-	+	+	+	3.2	+	3TC
HBVO-07	+	+	-	-	-	+	ND	+	-
HBVO-17	+	-	+	+	+	+	2.4	+	TDF
HBVO-22	+	+	-	+	+	+	ND	+	3TC
HBVO-27	+	+	+	+	+	+	ND	+	TDF/FTC
HBVO-31	+	+	+	+	+	+	4.3	+	3TC
HBVO-32	+	+	+	+	+	+	2.2	+	3TC
HBVO-36	+	-	-	+	+	+	4.3	+	-
HBVO-47	+	-	+	+	+	+	5.1	-	-
HBVO-49	+	+	+	+	+	+	ND	+	-
HBVO-54	+	+	+	+	+	+	3.6	+	TDF/FTC
HBVO-75	+	+	+	+	+	+	ND	+	TDF/FTC
SN
HBVO-03	-	-	-	+	+	+	5	O	-
HBVO-08	-	-	-	-	-	+	1.7	+	3TC
HBVO-18	-	-	-	+	+	+	2.6	+	-
HBVO-20	-	-	-	+	+	+	3.3	+	3TC
HBVO-26	-	-	-	+	+	+	3.9	+	-
HBVO-33	-	-	-	+	-	+	3	+	TDF
HBVO-34	-	-	-	+	+	+	2.7	+	-
HBVO-35	-	-	-	+	-	+	2.4	+	-
HBVO-38	-	-	-	+	-	+	ND	+	-
HBVO-39	-	-	-	+	+	+	ND	+	-
HBVO-45	-	-	-	+	+	+	ND	+	TDF
Frequency (%)						49

¹qPCR: Real time PCR utilizing SyberGreen assay;

²ARV treatment included tenofovir (TDF). HIV: Human immunodeficiency virus; HBV: hepatitis B virus; SP: Seropositive (one or more HBV serological marker: anti-HBc, anti-HBe, anti-HBs); SN: Negative for all HBV markers; ND: No detectable; S: Surface ORF; X: Protein X ORF; C: Core ORF; Tx: Treatment; TDF/FTC: Tenofovir/emtricitabine; 3TC: Lamivudine; O: Other ARV treatment (IFN).