Enhancement of BK channel activity with the BK channel opener NS-1619 significantly reduces the amplitude of eIPSCs of CeA neurons. A, Representative traces of eIPSCs at a holding potential of −70 mV before and after NS1619 application. In this neuron, bath application of NS1619 resulted in a reduction in the amplitude of eIPSCs to 39.8% of control, as demonstrated in A. B, Time course of the peak amplitude of eIPSCs during control and bath application of NS1619. C, Bar graph showing the mean change in the peak amplitude of eIPSCs after bath application of NS1619 (*p < 0.05; n = 6).