Table I. Description of clinical groups of P. falciparum and P. vivax infections.
The characteristics of the 9 clinical groups and the non-exposed donors are indicated, including the Plasmodium species detected, the abbreviation used to designate the group throughout the manuscript and a short description of the clinical group (PCR: asymptomatic donors with parasites detected by PCR, LM: asymptomatic donors with parasites detected by light microscopy, S: symptomatic donors, Pf:donors with detectable P. falciparum infection; Pv:donors with detectable P. vivax infection; Pf/Pv: donors with detectable P. falciparum and P. vivax infection); as well the mean and range of parasitemia values observed by LM, the result of the PCR test for parasitemia, the presence or absence of fever, the mean and range of the age of donors, the percentage of donors older than 5 years, and the number of donors in each group (N). * - all symptomatic samples are from a study that includes only children younger than 5 years; ^ - all malaria naïve controls are older than 18 years.
| Abbreviation | Clinical group | Mean parasitemia (range) | Parasitemia (by PCR) | Fever | Mean age, yrs (range) | % of donors > 5 Yrs | N | |
|---|---|---|---|---|---|---|---|---|
| Pf infection | Pf.PCR | Asymptomatic Pf infection, PCR+ | 0 (0–0) | Yes | No | 5.83 (2–9) | 65.5 | 29 |
| Pf.LM | Asymptomatic Pf infection, LM+ | 798.8 (40–2,015) | Yes | No | 6.21 (0–10) | 73.7 | 19 | |
| Pf.S | Symptomatic Pf infection | 85,480.0 (3,000–378,000) | Yes | Yes | 2.83 (1–5) | 0* | 40 | |
| Pv infection | Pv.PCR | Asymptomatic Pv infection, PCR+ | 0 (0–0) | Yes | No | 5.32 (0.5–10) | 50 | 20 |
| Pv.LM | Asymptomatic Pv infection, LM+ | 544.5 (80–1,482) | Yes | No | 4.90 (2–6) | 65 | 20 | |
| Pv.S | Symptomatic Pv infection | 21,622.40 (280–223,040) | Yes | Yes | 1.32 (0–4) | 0* | 50 | |
| Pf&Pv co-infection | Pf/Pv.PCR | Asymptomatic mixed infection, PCR+ | 0 (0–0) | Yes | No | 7.25 (2–10) | 83.3 | 12 |
| Pf/Pv.LM | Asymptomatic mixed infection, LM+ | Pf: 604.5 (40–2,180) | Yes | No | 5.87 (2–9) | 75 | 16 | |
| Pv: 381.9 (65–1,612) | ||||||||
| Pf/Pv.S | Symptomatic mixed infection | Pf: 112,073.3 (5,160–326,720) | Yes | Yes | 2.56 (1–4) | 0* | 18 | |
| Pv: 1966.7 (360–10,160) | ||||||||
| Non-exposed controls | Malaria naïve | 0 (0–0) | No | No | Adults | 100̂ | 18 | |