Table II. Proteins identified by iTRAQ as significantly more or less abundant in sym hemocytes.
| Trenda | Database I.D. | Protein | Pepb | Log2 fold changec | p value |
|---|---|---|---|---|---|
| More abundant | Meta990274633 | Cathepsin D | 39 | 1.054 | 1.20E-19 |
| Meta990279877 | Cathepsin L2 | 12 | 2.097 | 1.29E-05 | |
| Meta990255245 | Galectin 4-like protein transcript variant | 2 | 1.287 | 3.21E-02 | |
| Meta990274730 | Ganglioside GM2 activator precursor | 4 | 1.222 | 1.08E-03 | |
| Meta990237061 | Ganglioside GM2 activator precursor | 6 | 2.082 | 6.87E-04 | |
| Meta990280234 | Ganglioside GM2 activator precursor | 4 | 2.128 | 3.18E-02 | |
| Meta990084014 | Glucosamine-fructose-6-phosphate aminotransferase | 2 | 0.820 | 4.50E-02 | |
| Meta990256250 | Histone H4-I | 56 | 1.135 | 1.99E-34 | |
| Meta990272817 | 26S proteasome non-ATPase subunit 12 | 2 | 0.825 | 4.26E-02 | |
| Meta990275393 | Hypothetical protein BRAFLDRAFT 185672 | 5 | 0.829 | 4.33E-04 | |
| Meta990279786 | Pancreatic triacylglycerol lipase-like | 4 | 1.856 | 4.30E-03 | |
| Meta990297914 | Amino acid transport protein rBAT | 8 | 0.877 | 1.58E-03 | |
| Meta990261223 | Pyruvate carboxylase | 2 | 0.830 | 3.02E-02 | |
| Meta990234931 | Histone H3.2-like | 24 | 1.434 | 1.46E-12 | |
| Meta990123568 | Intermediate filament protein | 5 | 0.853 | 3.93E-03 | |
| Meta990236123 | Intermediate filament protein | 12 | 1.972 | 5.32E-05 | |
| Meta990244043 | l-3-hydroxyacyl-coenzyme a dehydrogenase | 4 | 0.862 | 4.43E-02 | |
| Meta990233579 | LeechCAM | 5 | 1.422 | 7.15E-04 | |
| Meta990279781 | Myosin heavy chain | 4 | 0.869 | 3.98E-02 | |
| Meta990231669 | Myosin heavy chain isoform B | 66 | 0.978 | 1.64E-25 | |
| Meta990231856 | Aconitate hydratase, mitochondrial-like | 4 | 1.078 | 6.88E-03 | |
| Meta990275031 | s-formylglutathione hydrolase-like | 5 | 0.812 | 3.57E-02 | |
| Meta990210359 | WW domain-containing oxidoreductase-like | 20 | 1.359 | 4.13E-14 | |
| Meta990236159 | WW domain-containing oxidoreductase-like | 4 | 1.603 | 8.54E-03 | |
| Meta990272315 | Rab3 | 3 | 1.176 | 2.51E-02 | |
| Less abundant | Meta990253072 | GM11222 | 5 | −0.844 | 2.56E-02 |
| Meta990275900 | Heat shock protein 22 isoform 1 | 7 | −0.975 | 2.13E-03 | |
| Meta990300071 | Hypothetical protein | 3 | −0.858 | 1.51E-03 | |
| Meta990081459 | Hypothetical protein | 8 | −1.341 | 2.30E-05 | |
| Meta990232278 | LIM domain and actin-binding protein 1 | 29 | −1.000 | 1.52E-14 | |
| Meta990297867 | Myosin regulatory light chain 2 | 26 | −0.856 | 8.14E-12 | |
| Meta990275793 | EsPGRP 5 | 25 | −1.023 | 4.71E-11 | |
| Meta990299707 | Calumenin-like | 3 | −1.227 | 9.64E-03 | |
| Meta990236998 | Calumenin-like | 6 | −0.988 | 1.08E-03 | |
| Meta990232620 | Dynactin 2-like | 6 | −1.045 | 1.13E-02 | |
| Meta990220758 | Hypothetical protein LOC100115922 | 3 | −1.474 | 1.23E-02 | |
| Meta990232946 | mps one binder kinase activator-like 2B | 3 | −0.807 | 2.46E-02 | |
| Meta990231811 | Rootletin-like | 2 | −0.904 | 1.35E-02 | |
| Meta990232518 | Protein kinase, AMP-activated, β 1 | 5 | −0.839 | 4.23E-03 | |
| Meta990274714 | Similar to surfactant B protein | 8 | −1.037 | 2.10E-03 | |
| Meta990255307 | THO complex 4-like | 3 | −1.444 | 3.91E-04 | |
| Meta990299300 | Translationally controlled tumor protein | 18 | −0.894 | 8.92E-07 | |
| Meta990139263 | Tropomyosin | 4 | −0.826 | 1.89E-02 |
a Protein trend based on iTRAQ data.
b Pep: number of peptides contributing to the iTRAQ ratio for that protein.
c Log2 fold change represents a protein difference in sym relative to cured.