Table 1.

Effect of INSTI-resistance mutations on the relative HIV-1 replication capacity based on reverse transcriptase activity in TZM-bl cells.

Backbone	Genotype of Mutation	RT Activity (% of WT)	95% Confidence Intervals
NL4.3	WT	100	89 to 113
	M184V (RT)	77	68 to 88
	E138K (IN)	46	42 to 51
	R263K (IN)	42	38 to 46
	E138K/R263K (IN)	37	34 to 40