Table 1.
Association among clinicopathological variables and THBS2 expression and overall survival of gastric cancer patients
| Variables | Negative | Positive | Total No. | Pvalue a | Overall survival OS | |
|---|---|---|---|---|---|---|
| Log-Rank P b | HR(95% CI) | |||||
| No.(%) | No.(%) | |||||
| Age (y) | 0.112 | 0.743 | ||||
| <61 | 24(38.1) | 39(61.9) | 63 | 1(reference) | ||
| ≥61 | 35(53.0) | 31(47.0) | 66 | 1.09(0.67-1.77) | ||
| Gender | 0.831 | 0.405 | ||||
| Male | 47(46.5) | 54(53.5) | 101 | 1(reference) | ||
| Female | 12(42.9) | 16(57.1) | 28 | 0.76(0.40-1.45) | ||
| Histological grade | 0.005 | 0.011 | ||||
| Well and moderate | 24(33.8) | 47(66.2) | 71 | 1(reference) | ||
| Poor and other | 35(60.3) | 23(39.7) | 58 | 1.89(1.16-3.09) | ||
| Tumor location | 0.419 | 0.204 | ||||
| Upper | 27(40.3) | 40(59.7) | 67 | 1(reference) | ||
| Middle | 15(53.6) | 13(46.4) | 28 | 1.66(0.86-3.18) | ||
| Lower | 17(50.0) | 17(50.0) | 34 | 1.90(0.90-4.01) | ||
| Depth of invasion | 0.271 | 0.001 | ||||
| T1-T2 | 9(34.6) | 17(65.4) | 26 | 1(reference) | ||
| T3-T4 | 50(48.5) | 53(51.5) | 103 | 11.60(2.83-47.45) | ||
| Lymph node metastasis | 0.454 | <0.001 | ||||
| Absent | 17(40.5) | 25(59.5) | 42 | 1(reference) | ||
| Present | 42(48.3) | 45(51.7) | 87 | 5.16(2.46-10.84) | ||
| TNM stage | 0.283 | <0.001 | ||||
| I-II | 21(39.6) | 32(60.4) | 53 | 1(reference) | ||
| III-IV | 38(50.0) | 38(50.0) | 76 | 7.14(3.52-14.49) | ||
Bold value is statistically significant at P < 0.05, HR hazard ratio.
a, P value of clinicopathological variables and THBS2 expression.
b, P value of association between clinicopathological variables and overall survival of gastric cancer patients.