Table 1.
Intravascular and angiographic imaging analyses at baseline and at 28-day follow-up following PCB delivery in porcine coronary arteries
| Crystalline coating (n=8) | Amorphous coating (n=9) | POBA control (n=9) | |
|---|---|---|---|
| QVA | |||
| Baseline | |||
| RVD (mm) | 3.09±0.1 | 3.00±0.1 | 3.05±0.1 |
| Stent to artery ratio | 1.46±0.1 | 1.35±0.1 | 1.48±0.1 |
| Balloon to artery ratio | 1.46±0.1 | 1.41±0.1 | 1.46±0.1 |
| Poststent MLD (mm) | 3.28±0.2 | 3.08±0.3 | 3.13±0.2 |
| OCT | |||
| 28-day follow-up | |||
| RVD (mm) | 2.69±0.3 | 2.65±0.2 | 2.60±0.2 |
| MLD (mm) | 1.62±0.6 | 1.41±0.3 | 1.25±0.7 |
| Diameter stenosis (%) | 38.8±24 | 46.9±10. | 51.8±25 |
| Lumen area (mm2) | 5.08±0.8* | 2.76±0.28 | 3.1±2.3 |
| Stent area (mm2) | 10.65±0.4 | 9.12±0.3† | 10.45±1 |
| Neointimal area (mm2) | 5.57±0.7 | 6.36±0.3 | 7.20±1.8 |
| Area stenosis (%) | 53.1±14* | 69.7±11 | 71.2±18 |
| Neointimal thickness (mm) | 0.63±0.1 | 0.80±0.1 | 0.80±0.2 |
*p<0.05 vs Amorphous and POBA.
†p<0.05 vs Crystalline and POBA.
MLD, minimal lumen diameter; OCT, optical coherence tomography; PCB, paclitaxel-coated balloons; POBA, plain balloon angioplasty; QVA, quantitative vessel analysis; RVD, reference vessel diameter.