Table 1.
Participant characteristics
| PiB-positive (n = 22) | PiB-negative (n = 41) | t-test/chi-square | P-value | |
|---|---|---|---|---|
| Male, % (n) | 59.1 (13) | 43.9 (18) | 1.32 | 0.25 |
| Age, mean (SD) | 44.3 (3.8) | 34.5 (5.2) | −7.5 | <0.001 |
| Race/ethnicity, % (n) | 0.58 | |||
| White | 95.5 (21) | 97.6 (40) | ||
| Asian | 0 (0) | 0 (0) | ||
| American Indian Alaska Native | 4.5 (1) | 0 (0) | ||
| More than one race | 0 (0) | 2.4 (1) | ||
| APOE statusa, % (n) | ||||
| E2/E2 | 4.8 (1) | 0.0 (0) | * | 0.78 |
| E2/E3 | 23.8 (5) | 25.0 (10) | ||
| E3/E3 | 61.9 (13) | 65.0 (26) | ||
| E3/E4 | 9.5 (2) | 7.5 (3) | ||
| E4/E4 | 0.0 (0) | 2.5 (1) | ||
| Current residence, % (n) | * | 0.22 | ||
| With family | 59.1 (13) | 63.4 (26) | ||
| Group home | 22.7 (5) | 9.8 (4) | ||
| Supported apartment | 9.1 (2) | 17.1 (7) | ||
| Independently | 9.1 (2) | 7.3 (3) | ||
| Other | 0 (0) | 2.4 (1) | ||
| Employment, % (n) | * | 0.65 | ||
| Full or part time with pay | 22.7 (5) | 36.6 (15) | ||
| Full or part time with support | 18.2 (4) | 17.1 (7) | ||
| Supported workshop | 36.4 (8) | 22.0 (9) | ||
| Volunteer | 13.6 (3) | 9.8 (4) | ||
| Day treatment program or not employed | 9.1 (2) | 14.6 (6) | ||
| Mental age equivalent in years, mean (SD) | 5.7 (1.5) | 5.6 (1.2) | −0.07 | 0.94 |
| PPVT age equivalent in years, mean (SD) | 7.9 (2.3) | 8.4 (3.7) | 0.77 | 0.45 |
| Medication, % (n) | ||||
| Hypothyroidism | 45.5 (10) | 58.5 (24) | 0.99 | 0.32 |
| Hypertension | 0.0 (0) | 7.3 (3) | * | 0.55 |
| Antipsychotic | 27.3 (3) | 6.3 (2) | * | 0.10 |
| Antidepressant/anti-anxiety | 27.3 (3) | 25.0 (8) | * | 1.0 |
| Mood/behaviour stabilizer | 0.0 (0) | 3.1 (1) | * | 1.0 |
| Narcotic pain reliever | 9.1 (1) | 0.0 (0) | * | 1.0 |
| Cholesterol | 27.3 (3) | 3.1 (1) | * | 0.046 |
aApoE status was not obtained for two subjects.
*No chi-square statistics is reported as Fisher's exact test was used to calculate probability due to sparsity.
PPVT = Peabody Picture Vocabulary Test.