Table 2.
One-way ANOVA comparing scores on neuropsychological measures between the PiB-positive versus PiB-negative group
| Neuropsychiatric measure | Unadjusted |
Adjusted by mental age |
Adjusted by chronological age and mental age |
|||||
|---|---|---|---|---|---|---|---|---|
| PiB-positive mean (SD) | PiB-negative mean (SD) | PiB-positive mean (SD) | PiB-negative mean (SD) | P-value | PiB-positive mean (SD) | PiB-negative mean (SD) | P-value | |
| Vineland | 180.2 (53.5) | 185.6 (46.1) | 179.9 (8.4) | 185.8 (6.2) | 0.57 | 184.6 (10.7) | 183.2 (7.1) | 0.92 |
| Free Recall Total | 14.2 (5.5) | 16.9 (6.4) | 14.0 (1.2) | 17.0 (0.9) | 0.05 | 14.9 (1.5) | 16.6 (1.0) | 0.42 |
| Free and Cued Recall Total | 30.7 (6.3) | 33.2 (5.8) | 30.6 (1.3) | 33.2 (0.9) | 0.10 | 31.4 (1.7) | 32.8 (1.1) | 0.54 |
| Cued Recall Intrusion | 4.1 (5.3) | 1.9 (2.9) | 4.2 (0.9) | 1.8 (0.6) | 0.03 | 3.5 (1.1) | 2.2 (0.7) | 0.40 |
| Block Design Total | 26.6 (8.1) | 28.2 (9.8) | 26.6 (1.7) | 28.3 (1.2) | 0.42 | 29.5 (2.0) | 26.7 (1.3) | 0.31 |
| Severe Impairment Battery | 46.0 (4.0) | 47.1 (3.6) | 46.0 (0.5) | 47.1 (0.4) | 0.10 | 46.4 (0.7) | 46.9 (0.4) | 0.59 |
| Visual Attention Accuracy Time | 94.2 (47.5) | 77.0 (35.4) | 94.5 (7.2) | 76.8 (5.3) | 0.05 | 88.3 (9.1) | 80.1 (6.1) | 0.51 |
| Visual Attention Accuracy | 16.0 (8.3) | 18.3 (2.8) | 15.9 (1.1) | 18.3 (0.8) | 0.08 | 16.9 (1.4) | 17.8 (0.9) | 0.63 |
| Verbal Fluency Raw | 23.5 (11.0) | 24.6 (9.4) | 23.5 (1.7) | 24.7 (1.3) | 0.58 | 22.8 (2.2) | 25.0 (1.5) | 0.46 |
| Verbal Fluency Repetitions | 3.2 (3.4) | 2.0 (2.1) | 3.2 (0.6) | 2.0 (0.4) | 0.08 | 3.3 (0.7) | 2.0 (0.5) | 0.19 |
| Purdue Pegboard – Single hands | 13.9 (3.3) | 15.2 (3.6) | 13.9 (0.7) | 15.2 (0.5) | 0.14 | 14.6 (0.9) | 14.8 (0.6) | 0.85 |
| Purdue Pegboard Both hands | 4.7 (1.9) | 5.7 (1.9) | 4.7 (0.4) | 5.7 (0.3) | 0.05 | 5.3 (0.5) | 5.4 (0.3) | 0.94 |
| Story Recall Initial | 1.9 (2.1) | 2.4 (2.1) | 1.9 (0.3) | 2.4 (0.3) | 0.20 | 1.9 (0.4) | 2.4 (0.3) | 0.38 |
| Story Recall Initial – Delayed | 3.5 (3.2) | 3.2 (2.8) | 3.5 (0.5) | 3.2 (0.4) | 0.63 | 3.5 (0.7) | 3.2 (0.4) | 0.76 |
| Expressive One Word | 66.1 (22.5) | 77.4 (25.8) | 65.9 (4.0) | 77.5 (2.9) | 0.02 | 67.8 (5.1) | 76.5 (3.4) | 0.21 |
| PPVT age equivalent | 93.7 (27.6) | 100.6 (44.2) | 93.4 (6.2) | 100.8 (4.6) | 0.34 | 101.2 (7.8) | 96.6 (5.2) | 0.66 |
| Rivermead Picture Recognition | 4.4 (3.5) | 6.5 (3.2) | 4.3 (0.6) | 6.5 (0.5) | 0.01 | 5.5 (0.8) | 5.9 (0.5) | 0.70 |
| VMI age equivalent | 17.1 (2.9) | 16.9 (3.0) | 17.1 (0.5) | 16.9 (0.4) | 0.79 | 17.8 (0.7) | 16.6 (0.4) | 0.18 |
| Cat and Dog Switch trial errors | 3.6 (5.3) | 1.7 (3.8) | 3.6 (0.8) | 1.7 (0.6) | 0.07 | 1.9 (1.0) | 2.6 (0.7) | 0.61 |
| Cat and Dog Switch time | 11.7 (10.3) | 9.4 (8.3) | 11.7 (1.8) | 9.4 (1.4) | 0.32 | 13.3 (2.3) | 8.5 (1.6) | 0.14 |
| Corsi Total Forward | 12.7 (7.0) | 12.0 (8.6) | 12.7 (1.6) | 12.1 (1.2) | 0.76 | 14.9 (2.0) | 10.9 (1.3) | 0.15 |
| Corsi Total Backward | 3.1 (3.6) | 4.2 (4.4) | 3.1 (0.8) | 4.2 (0.6) | 0.29 | 4.6 (1.0) | 3.4 (0.6) | 0.35 |
| Digit Span Total Forward | 11.0 (6.0) | 11.7 (7.2) | 10.9 (1.2) | 11.8 (0.9) | 0.59 | 10.9 (1.6) | 11.8 (1.1) | 0.69 |
| Digit Span Total Backward | 4.7 (5.0) | 5.2 (5.1) | 4.6 (0.9) | 5.2 (0.6) | 0.62 | 5.1 (1.1) | 4.9 (0.7) | 0.89 |
PPVT = Peabody Picture Vocabulary Test; VMI = Developmental Test of Visual-Motor Integration-5th Edition.