Table 6.
Multivariate logistic regression analysis of risk factors of atrophic gastiritis and intestinal metaplasia in total population
| Variable | Antral AG | Antral IM | Corporal AG | Corporal IM | ||||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| Adjusted OR (95% CI) | P-value | Adjusted OR (95% CI) | P-value | Adjusted OR (95% CI) | P-value | Adjusted OR (95% CI) | P-value | |
| Aging by 5-year | 1.25 (1.11–1.42) | <0.001 | 1.25 (1.10–1.42) | 0.001 | 1.25 (1.09–1.44) | 0.002 | 1.26(1.11–1.44) | 0.001 |
| FDR | 1.22 (0.75–2.00) | 0.42 | 1.50 (0.93–2.42) | 0.097 | 1.01 (0.60–1.71) | 0.96 | 1.31 (0.79–2.16) | 0.30 |
| H. pylori infected | 9.28 (4.73–18.18) | <0.001 | 7.81 (3.72–16.40) | <0.001 | 4.46 (2.16–9.22) | <0.001 | 3.00 (1.49–5.89) | 0.002 |
| Male | 1.22 (0.72–2.07) | 0.47 | 1.04 (0.62–1.74) | 0.87 | 1.31 (0.59–2.91) | 0.51 | 1.07 (0.62–1.86) | 0.80 |
| Severely spicy diet | 1.54 (0.92–2.58) | 0.10 | 2.28 (1.36–3.84) | 0.002 | ||||
| Severely salty diet | 1.48 (0.85–2.58) | 0.17 | 1.14 (0.66–1.97) | 0.64 | ||||
| Current or ex-smoker | 0.43 (0.18–1.01) | 0.051 | ||||||
| Rural raised | 1.40 (0.86–2.26) | 0.17 | 1.36 (0.83–2.25) | 0.226 | ||||
| Monthly income<US $5000 | 1.20 (0.66–2.15) | 0.55 | ||||||
| Final education compared to university education | ||||||||
| Elementary | 0.99 (0.60–1.63) | 0.95 | 1.39 (0.79–2.46) | 0.29 | ||||
| Middle-high | 1.23 (0.50–3.03) | 0.66 | 0.93 (0.33–2.63) | 0.88 | ||||
| Nagelkerke’s R2 | 0.286 | 0.236 | 0.167 | 0.104 | ||||
| Hosmer-Lemeshow Goodness-of-fit test, P-value | 0.764 | 0.487 | 0.228 | 0.199 | ||||
FDR, first degree relatives of gastric cancer; AG, atrophic gastritis; IM, intestinal metaplasia. For each column of data, sex, FDR and variables with P<0.2 were entered into the model.