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. 2013 Sep;18(3):249–256. doi: 10.15430/JCP.2013.18.3.249

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Copyright © 2013 Korean Society of Cancer Prevention

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 4. — Morin up-regulates HO-1 via phosphorylation of ERK. Cells were treated with morin for various times. (A) Western blot were performed to detect expression of ERK. ^*Significantly different from control cells (P<0.05). Cells were pre-incubated with inhibitor-U0126 (2.5 μM) for 1 h and the protein was analyzed by (B) western blot and (C) DNA binding activity was detected by EMSA. ^*Significantly different from control cells (P<0.05). ^**Significantly different from morin-treated cells (P<0.05). (D) Cells were pre-incubated with U0126 for 1 h, and after incubation of 8 h, the HO-1 expression was analyzed by western blot. *Significantly different from control cells (P<0.05). ^**Significantly different from morin-treated cells (P<0.05).