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. 2014 Sep;51(3):380–390. doi: 10.1165/rcmb.2013-0043OC

Figure 2.

Figure 2.

Immunohistochemistry (IHC) of extracellular superoxide dismutase (SOD)3 in RA- versus O2-exposed mice. (A) Brown 3,3'-diaminobenzidine staining denotes positive staining of SOD3 on 20× and 40× magnification. Representative images of RA-exposed mice demonstrate continuous staining of SOD3 along the extracellular matrix, whereas O2-exposed (5 d) mice demonstrate fragmented and decreased deposition of SOD3 along the extracellular matrix. (B) Quantitative IHC confirms reduced SOD3 deposition in O2-exposed lungs (n = 3 per group) (P = 0.026).