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. 2014 Oct 3;15:105. doi: 10.1186/s12863-014-0105-8

Table 1.

Average imputation accuracy from the bovine 777 K SNP chip to whole-genome sequence on chromosome 1 and 29

Chromosome 1 Chromosome 29
HOL20 MIX80 HOL80 MIX140 HOL20 MIX80 HOL80 MIX140
Sequence (n) 1,912,451 1,912,451 1,91,2451 1,912,451 670,773 670,773 670,773 670,773
777 K chip (n) 41,868 41,868 41,868 41,868 13,556 13,556 13,556 13,556
No variation in reference set (n)1 1,178,683 710,480 894,633 616,808 385,137 221,137 283,516 187,904
No variation observed in validation set (n)1 2 468,203 284,050 561,875 2 164,000 101,621 197,233
No variation imputed in validation set (n)1 19,484 1,005 1,077 649 19,284 4,139 4,267 3,681
Obtained overall imputation accuracy (n) 672,416 690,895 690,823 691,251 252,796 267,941 267,813 268,399
average overall imputation accuracy (r) 0.70 0.83 0.88 0.89 0.59 0.74 0.80 0.82
standard deviation of r 0.32 0.27 0.25 0.24 0.37 0.32 0.29 0.28

1No variation was present in the genotype dosages of at least one of the 5 corresponding cross-validation sets, therefore the imputation accuracy (correlation) could not be computed.

2In scenario HOL20 the reference sets were the same as the validation sets, therefore all variants without variation in at least one cross-validation reference set are the same as the variants without variation in observed genotypes of the validation sets.