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. 2014 Sep 18;16(5):427. doi: 10.1186/s13075-014-0427-y

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© Nagai et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Comparison of relative gene expression levels between the osteoarthritis (OA) and intravenous administration of bevacizumab in OA (OAB IV) groups (experiment 2). (A) Synovial gene expression. (B) Subchondral bone gene expression. (C) Articular cartilage gene expression. The y-axis is defined as follows: 2^–ΔCT OA or OAB IV target gene/2^–ΔCT normal target gene. The normal tissue is represented as 1 on the y-axis. Data are expressed as mean ± SD (n = 4 knees). *P <0.05 by the Mann-Whitney U-test.