Table 2.

Gout Management Agents²

Phase	Drug	Dose
Acute gout	Nonsteroidal anti-inflammatory drugs	Indomethacin (Indocin): 25–50 mg four times daily Naproxen (Naprosyn): 500 mg twice daily Ibuprofen (Motrin): 800 mg four times daily Sulindac (Clinoril): 200 mg twice daily
	Colchicine	1.2 mg orally initially, 0.6 mg orally one hour later
	Corticosteroids	Prednisone: 0.5 mg/kg orally on day 1; taper by 5 mg each day thereafter Triamcinolone acetonide (Kenalog): 60 mg intramuscularly; repeat in 24 hours if necessary
Intercritical gout	Colchicine	0.6 mg orally once or twice daily
Chronic tophaceous gout (prophylaxis)	Sulfinpyrazone	50 mg three times daily initially; gradually titrate up until serum urate is < 6 mg/dL; maximum 800 mg per day
	Probenecid	250 mg twice daily initially; gradually titrate up until serum urate is < 6 mg/dL; maximum 3 g per day
	Allopurinol	50–100 mg daily; gradually titrate up until serum urate is < 6 mg/dL; typical dosage 200–300 mg daily
	Febuxostat	40 mg daily initially, titrating up to 80 mg daily