Table 1.
Vaccine | Description | Adjuvants | Setting | NCT # |
---|---|---|---|---|
Algenpantucel-L | Alpha-1,3-galactosyltransferase-expressing allogeneic pancreatic tumor cell vaccine | None | Adjuvant | NCT01072981 |
Belagenpumatucel-L | Contains NSCLC tumor cells | TGF-β2 antisense | Adjuvant | NCT00676507 |
E75 peptide + GM-CSF vaccine | HLA A2/A3-restricted HER-2/neu peptide vaccine | GM-CSF | Prevention | NCT01479244 |
Emepepimut-S | Liposomal BLP25 vaccine | MPL | Adjuvant | NCT01015443 |
Fowlpox-PSA-TRICOM vaccine | Recombinant fowlpox vaccine encoding prostate-specific antigen | TRICOM (B7.1, ICAM-1 and LFA-3) | Adjuvant | NCT01322490 |
GV1001 | Contains telomerase peptide | GM-CSF | Adjuvant | NCT00925548 |
HPV 16/18 L1 viruslike particle vaccin0065 | Different formulation from Cervarix developed by Xiamen Innovax Biotech | Alum | Prevention | NCT01735006 |
HPV 16/18 L1 viruslike particle/AS04 vaccine | AS04 (Alum +MPL) | Prevention |
NCT00637195 NCT01381575 NCT00799825 NCT00849381 NCT00779766 NCT01190189 NCT00929526 NCT01249365 NCT01627561 NCT01277042 NCT00811798 NCT00652938 NCT01190176 NCT00877877 NCT00947115 NCT01418937 NCT00937950 |
|
HPV vaccine V503 | Contains L1 capsid proteins for nine HPV strains | Amorphous aluminum hydroxyphosphate sulfate | Prevention |
NCT01651949 NCT01047345 NCT00943722 NCT01254643 NCT01073293 NCT00988884 |
IMA901 | Contains ten renal cell carcinoma associated peptide antigens | GM-CSF | Nonadjuvant | NCT01265901 |
POL-103A | Contains purified antigens from melanoma cell lines | Alum | Adjuvant | NCT01546571 |
Polyvalent antigen-KLH conjugate vaccine | Contains globo H, GM2 ganglioside, Tn-MUC1, TF, and sTn | OPT-821 (purified, natural saponin) | Adjuvant | NCT00693342 |
Quadrivalent HPV (types 6, 11, 16, 18) recombinant vaccine | Amorphous aluminum hydroxyphosphate sulfate | Prevention (4), precancerous (1) |
NCT00964210 NCT01245764 NCT01461096 NCT01375868 NCT00496626 |
|
Racotumomab | Anti-P3 antibody idiotype monoclonal antibody 1E10 | Alum | Adjuvant | NCT01460472 |
Vaccinia-PSA-TRICOM vaccine | Recombinant vaccinia vaccine encoding prostate-specific antigen | TRICOM (B7.1, ICAM-1 and LFA-3) | Adjuvant | NCT01322490 |
Abbreviations: HPV, human papillomavirus; GM-CSF, granulocyte macrophage colony-stimulating factor; MPL, monophosphoryl lipid A; TGF-β, transforming growth factor beta; NCT, National Clinical Trial; NSCLC, non-small-cell lung cancer.