Table 2.

Effect of treatment with AM 30 mg/kg, AM 60 mg/kg and tamoxifen on tumor volume (mm³) in experimental breast cancer in rats

Treatment groups	Tumor volume (mm3)	Reduction of tumor percentage (%)
Normal control	–	–
Mammary tumor control	1,773±563	–
AM 30 mg/kg LD	460±33.5*	74.1%*
AM 60 mg/kg HD	372±24.6*	79.2%*
Tamoxifen 10 mg/kg	290±21*	83.6%*
AM 60 mg/kg	–	–

Notes: Each value represents mean ± SD of given number of animals (n=5). The statistical significance is expressed as *P<0.05.

Abbreviations: AM, α-Mangostin; LD, low dose; HD, high dose; SD, standard deviation.