Table 3.
Comparison of post-resuscitation care and outcomes between the mECPR and mCCPR groups
| mECPR (n = 52) | mCCPR (n = 52) | P -value | |
|---|---|---|---|
| Rate of ROSB/ROSC (≥20 minutes), n (%) | 42 (80.8) | 20 (38.5) | < 0.001 |
| Therapeutic hypothermia, n (%) | 14 (26.9) | 12 (23.1) | 0.821 |
| CAG in patients with suspected ACS (%) | 39 in 44 (88.6) | 11 in 15 (73.3)* | 0.213 |
| CAG findings | n = 39 | n = 11 | 0.010 |
| No significant coronary lesion | 5 (12.8) | 4 (36.4) | |
| Coronary spasm | 3 (7.7) | 4 (36.4) | |
| Presence of coronary occlusion/stenosis, n (%) | 31 (79.5) | 3 (27.3) | |
| Diseased coronary artery, n (%) | n = 31 | n = 3 | 0.603 |
| 1 vessel | 23 (74.2) | 3 (100) | |
| 2 vessels | 5 (16.1) | 0 (0) | |
| 3 vessels | 3 (9.7) | 0 (0) | |
| PCI for coronary occlusion/stenosis | 29 (93.5) | 3 (100) | 1.000 |
| CPC score at discharge | 0.011 | ||
| 1, n (%) | 7 (13.5) | 1 (1.9) | |
| 2, n (%) | 1 (1.9) | 0 | |
| 3, n (%) | 0 | 2 (3.8) | |
| 4, n (%) | 1 (1.9) | 8 (15.4) | |
| 5, n (%) | 43 (82.7) | 41 (78.8) | |
| Hospital LOS in survival to discharge, days | 30 (14 to 60) | 28 (16 to 50) | 0.766 |
| CPC score at 3 months post arrest | 0.070 | ||
| 1, n (%) | 7 (13.5) | 1 (1.9) | |
| 2, n (%) | 1 (1.9) | 0 (0) | |
| 3, n (%) | 0 (0) | 2 (3.8) | |
| 4, n (%) | 0 (0) | 1 (1.9) | |
| 5, n (%) | 44 (84.6) | 48 (92.3) | |
| Final diagnosis of arrest, n (%) | < 0.001 | ||
| Cardiac | |||
| ACS/AMI | 36 (69.2) | 9 (17.3) | |
| Lethal arrhythmia | 3 (5.8) | 5 (9.6) | |
| HF, HCMP, DCMP | 3 (5.8) | 2 (3.8) | |
| Pulmonary embolism | 2 (3.8) | 1 (1.9) | |
| Unknown sudden arrest | 4 (7.7) | 31 (59.6) | |
| Non-cardiac | |||
| Respiratory arrest | 1 (1.9) | 0 (0) | |
| Hypothermia | 1 (1.9) | 0 (0) | |
| Acute kidney injury | 1 (1.9) | 3 (5.8) | |
| Brain hemorrhage | 1 (1.9) | 1 (1.9) | |
| Causes of death at 3 months post arrest, n (%) | n = 44 | n = 48 | < 0.001 |
| No ROSB or ROSC | 10 (22.7) | 32 (66.7) | |
| Refractory shock | 24 (54.5) | 4 (8.4) | |
| Hypoxic brain injury and organ failure | 8 (18.2) | 12 (25.0) | |
| Brain death | 2 (4.5) | 0 (0) |
Data are shown as median (IQR) or number (%). *In 15 suspected ACS patients with ROSC (≥20 minutes). CPR, cardiopulmonary resuscitation; ECPR, extracorporeal CPR; CCPR, conventional CPR; ROSB, return of spontaneous heart beat; ROSC, return of spontaneous circulation; CAG, coronary angiography; ACS, acute coronary syndrome; PCI, percutaneous coronary intervention; CPC, cerebral performance category; LOS, length of stay; HF, heart failure; HCMP, hypertrophic cardiomyopathy; DCMP, dilated cardiomyopathy.