Table 5.
Comparison of post-ECPR care according to the neurologic outcome in the mECPR group (n = 52)
| CPC 1, 2 (n = 8) | CPC 3 to 5 (n = 44) | P -value | |
|---|---|---|---|
| ROSB after ECPR | 8 (100) | 34 (81.0) | 0.328 |
| MAP ≥60 mmHg within 2 hrs after ECPR, n (%) | 8 (100) | 25 (56.8) | 0.021 |
| Number of infused vasopressor/inotropics, n | 2 (1 to 3) | 2 (1 to 2) | 0.945 |
| Inotropic equivalent, μg/kg/min for 2 hrs post ECPR | 32 (10 to 74) | 59 (15 to 82) | 0.180 |
| LVEF after ECPR implantation | 33 (18 to 48) | 10 (0 to 20) | 0.009 |
| Therapeutic hypothermia, n (%) | 5 (62.5) | 9 (20.5) | 0.025 |
| ROSB to target temperature (33 °C), hrs | 4 (2 to 6) | 2.8 (1.6 to 3.0) | 0.222 0.435 |
| Time on target temperature, hrs | 24 (21 to 24) | 24 (24 to 41) | |
| CAG in patients with suspected ACS, n (%) | 7 in 7 (100) | 32 in 37 (86.5) | 0.574 |
| CAG findings | n =7 | n = 32 | 0.015 |
| No significant coronary lesion | 2 (28.6) | 3 (9.4) | |
| Coronary spasm, n (%) | 0 (0) | 3 (9.4) | |
| Coronary occlusion/stenosis, n (%) | 5 (71.4) | 26 (81.2) | |
| Diseased coronary artery, n (%) | n = 5 | n = 26 | 0.719 |
| 1 vessel | 4 (80.0) | 19 (73.1) | |
| 2 vessels | 1 (20.0) | 4 (15.4) | |
| 3 vessels | 0 (0) | 3 (11.5) | |
| PCI for coronary occlusion/stenosis | 5 (100) | 24 (92.3) | 1.000 |
| Complications during ECLS, n (%) | 0 (0) | 16 (36.4) | 0.047 |
| Bleeding at access site | - | 12 (27.3) | |
| Lower limb ischemia | - | 3 (6.8) | |
| Intracranial hemorrhage | - | 1 (2.3) | |
| Anterograde reperfusion catheter, n (%) | 11 ( 25.0) | 2 (25.0) | 1.000 |
| Amount of transfused pRBC | 5 (3 to 12) | 5 (1 to 10) | 0.833 |
| Successful weaning form ECLS, n (%) | 8 (100) | 2 (4.5) | <0.001 |
| Duration of ECLS, hrs | 43.6 (29.7 to 92.8) | 17.9 (3.7 to 48.7) | 0.026 |
Data are shown as median (IQR) or number (%). CPR, cardiopulmonary resuscitation; ECPR, extracorporeal CPR; ROSB, return of spontaneous heart beat; LVEF, left ventricle ejection fraction; CAG, coronary angiography; ACS, acute coronary syndrome; PCI, percutaneous coronary intervention; ECLS, extracorporeal life support; pRBC, packed red blood cells.