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. 2014 Oct 7;16(1):85. doi: 10.1186/s12968-014-0085-x

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© Mikami et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Patient example of raw Late Gadolinium Enhanced (LGE) image (Panel A), manual expert segmentation (Panel B) versus full width at half maximum (FWHM) -based segmentation (Panel C) and the Signal Threshold versus Reference Mean (STRM) -based segmentation at >3SD (Panel D), >4SD (Panel E) and >5SD thresholds (Panel F). A significant under-estimation of visually identifiable LGE is evident using the FWHM method.