Table 4.
Primary and sensitivity analyses of the Active Plus intervention conditions at the 12-month follow-up
| C | PB | PE | WB | WE | ICER b | CEAF d and probability highest NMB | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Costs a | Effect | Costs a | Effect | Costs a | Effect | Costs a | Effect | Costs a | Effect | |||
| Primary analysis | ||||||||||||
| PA (MET-hours/week) | 2760 (5301) | -2.2 | 2472 (4269) | 3.0 | 2295 (4694) | 2.7 | 3078 (6301) | 0.7 | 2504 (5666) | -0.4 | 555 (PE vs PB) | <€1000 PE, >€1000 PBPB: 50%; PE: 43% |
| QALY-EQ-5D-3Lc | 2739 (5293) | 0.884 | 2424 (4212) | 0.876 | 2305 (4642) | 0.883 | 3103 (6378) | 0.883 | 2528 (5730) | 0.888 | 40426 (PE vs WE) | <€40000 PE, >€40000 WE; PE: 45% |
| Sensitivity analyses | ||||||||||||
| 6-month follow-up | ||||||||||||
| PA (MET-hours/week) | 1444 (2988) | 7.4 | 1329 (2880) | 11.5 | 1106 (2456) | 15.6 | 1501 (3207) | 13.9 | 1201 (2663) | 8.1 | PE dominant | PE at any threshold; PE: 74% |
| QALY-EQ-5D-3Lc | 1442 (2985) | 0.442 | 1307 (2860) | 0.438 | 1106 (2426) | 0.441 | 1547 (3305) | 0.442 | 1211 (2683) | 0.444 | 38110 (PE vs WE) | <€45000 PE, >€45000 WE; PE: 56% |
| Complete cases | ||||||||||||
| PA (MET-hours/week) | 2382 (3880) | -2.5 | 2592 (4666) | 6.3 | 2316 (4986) | 5.7 | 2824 (5241) | 1.7 | 2217 (3316) | 4.1 | 472 (PE vs PB) | <€50 WE, >€50 < €400 PE, >€400 PB; PB: 44% |
| QALY-EQ-5D-3Lc | 2488 (4212) | 0.902 | 2423 (4452) | 0.878 | 2166 (4668) | 0.898 | 2635 (5031) | 0.893 | 2198 (3774) | 0.892 | PE dominant | PE at any threshold; PE: 46% |
| Baseline correction | ||||||||||||
| PA (ME- hours/week) | 2862 (3742) | -2.2 | 2664 (3277) | 3.0 | 2614 (3824) | 2.7 | 3038 (4593) | 0.7 | 2794 (4618) | -0.5 | 157 (PE vs PB) | <€175 PE, >€175 PB; PB: 54% |
| QALY-EQ-5D-3Lc | 2851 (3737) | 0.884 | 2633 (3252) | 0.876 | 2622 (3811) | 0.883 | 3045 (4643) | 0.883 | 2795 (4667) | 0.888 | 31308 (PE vs WE) | <€30000 PE, >€30000 WE; PE: 38% |
| Health care perspective | ||||||||||||
| PA (MET-hours/week) | 1693 (4093) | -2.2 | 1441 (2817) | 3.0 | 1297 (3340) | 2.7 | 1438 (2658) | 0.7 | 1419 (3963) | -0.4 | 452 (PE vs PB) | <€400 PE, >€400 PB; PB: 53% |
| QALY-EQ-5D-3Lc | 1670 (4082) | 0.884 | 1386 (2729) | 0.876 | 1287 (3256) | 0.883 | 1428 (2664) | 0.883 | 1386 (3965) | 0.888 | 17966 (PE vs WE) | <€12500 PE, >€12500 WE; WE: 42% |
| Other outcome measures | ||||||||||||
| Minutes MVPA/week | 2749 (5264) | -72.1 | 2463 (4241) | 3.1 | 2306 (4696) | 37.7 | 3078 (6301) | -32.8 | 2504 (5666) | -39.8 | PE dominant | PE at any threshold; PE: 83% |
| Days with sufficient PA | 2720 (5349) | 0.1 | 2520 (4303) | 0.4 | 2341 (4740) | 0.5 | 3076 (6286) | 0.0 | 2503 (5645) | 0.2 | PE dominant | PE at any threshold; PE: 76% |
| QALY-EQ-5D-3L UK tariff | 2739 (5293) | 0.858 | 2424 (4212) | 0.846 | 2305 (4642) | 0.856 | 3103 (6378) | 0.857 | 2528 (5730) | 0.864 | 25001 (PE vs WE) | <€25000 PE, >€25000 WE; PE: 42% |
PB = printed basic intervention, PE = printed environmental intervention, WB = Web-based basic intervention, WE = Web-based environmental intervention, C = control group.
aIn Euros; bcalculated according to the formula ICER = (Ci-Cc)/ (Ui-Uc); cBased on the Dutch algorithm for the EuroQol (EQ-5D-3L) scores; dCost-effectiveness acceptability frontiers (CEAF); eProbability of highest net monetary benefit (NMB) based on WTP = €20,000.