Table 1.
Comparison between patients with prescription for anticoagulants versus without
| Total cohort | Prescription for OA | Non-Prescription for OA | P | OR* (95% CI) | |
|---|---|---|---|---|---|
| (n = 1.828) 100% | (n = 827) 45,24% | (n = 1.001) 54,76% | |||
| Age (years) median/mean (SD) | 77.61 (±8.6) | 75.01 (±8.1) | 79.75 (±8.5) | < 0.001 | |
| < 65 years | 126 (6.9%) | 79 (9.6%) | 47 (4.7%) | < 0.001 | 2.14 (1.48-3.11) |
| 65-75 years | 537 (29.4%) | 323 (39.1%) | 214 (21.4%) | < 0.001 | 2.36 (1.99-2.90) |
| > 75 years | 1165 (63.7%) | 425 (51.4%) | 740 (73.9%) | < 0.001 | 0.37 (0.31-0.45) |
| Sex | |||||
| Male | 764 (41.8%) | 398 (48.1%) | 366 (36.6%) | < 0.001 | ref. category |
| Female | 1064 (58.2%) | 429 (51.9%) | 635 (63.4%) | < 0.001 | 0.62 (0.52-0.75) |
| Risk factors | |||||
| Hypertension | 1444 (79.0%) | 660 (79.8%) | 784 (78.3%) | 0.4 | 1.09 (0.87-1.37) |
| Diabetes mellitus | 530 (29.0%) | 240 (29.0%) | 290 (29.0%) | 0.9 | 1.00 (0.82-1.23) |
| Diagnosis | |||||
| TIA | 639 (35.0%) | 260 (31.4%) | 379 (37.9%) | < 0.001 | 0.75 (0.62-0.91) |
| Previous stroke | 433 (23.7%) | 179 (21.6%) | 254 (25.4%) | 0.062 | 0.81 (0.65-1.01) |
| mRS as assessed on discharge | |||||
| 0 | 557 (30.5%) | 282 (34.1%) | 275 (27.5%) | 0.002 | 1.37 (1.19-1.67) |
| 1 | 478 (26.1%) | 226 (27.3%) | 252 (25.2%) | 0.3 | 1.18 (0.91-1.38) |
| 2 | 403 (22.0%) | 174 (21.0%) | 229 (22.9%) | 0.3 | 0.90 (0.72-1.12) |
| 3 | 390 (21.3%) | 145 (17.5%) | 245 (24.5%) | < 0.001 | 0.66 (0.52-0.82) |
| Median, range | 1 (0–3) | 1 (0–3) | 1 (0–3) | ||
| Treatment in a neurological department | 1243 (68.0%) | 611 (73.9%) | 632 (63.1%) | < 0.001 | 1.65 (1.35-2.02) |
| Comorbidities occurring while hospitalisation | |||||
| Intracranial bleeding | 8 (0.4%) | 5 (0.6%) | 3 (0.3%) | 0.3 | 2.02 (0.48-8.49) |
| Extracranial bleeding | 7 (0.4%) | 4 (0.5%) | 3 (0.3%) | 0.5 | 1.61 (0.36-7.24) |
| Recurrent stroke/TIA | 17 (0.9%) | 12 (1.5%) | 5 (0.5%) | 0.04 | 2.93 (1.03-8.36) |
| Seizure | 6 (0.3%) | 0 (0%) | 6 (0.6%) | 0.03 | not applicable |
| Pneumonia | 42 (2.3%) | 18 (2.2%) | 24 (2.4%) | 0.8 | 0.91 (0.49-1.69) |
| Documented dementia within the insurance database # | 241 (13.2%) | 67 (7.2%) | 174 (14.2%) | < 0.001 | 0.42 (0.31-0.56) |
*Value calculated in a Chi Square Test of Independence.
#dementia documented within the insurance database on discharge or within 90 days after discharge; considered were the following ICD10 codes: dementia by Alzheimer’s disease (F00.-), vascular dementia (F01.-, G30), secondary dementia (F02.-) and undetermined dementia (F.03).
AK refers to anticoagulants.
TIA refers to transient ischaemic attack.
mRS refers to modified Rankin scale.