Table 2. Substitution ratios of bus-4 Ce core-I glycans differ from wild type.
| Substituent Ratio Type | N2 Substituent Ratio (mol/mol core-I saccharide)a , b | bus-4 Substituent Ratio (mol/mol core-I saccharide)a , b | % Difference relative to N2c |
| Glcβ1-4,6Gal | 1.02 (±0.024) | 0.89 (±0.023) | −5.8 (±4.7) |
| Glc/Galβ1-6GalNAc | 0.92(±0.029) | 0.95 (±0.021) | 7.03 (±4.9) |
| Glcβ1,4GalNAc | 0.45 (±0.010) | 0.64 (±0.011) | 38.5 (±5.14) |
| GlcA1,4GalNAc | 0.2203 (±0.004) | 0.16 (±0.004) | −42.2 (±12.2) |
| GlcAβ1,3Gal | 0.1815 (±0.015) | 0.075 (±0.015) | −30.0 (±22.7) |
a
Total molar ratios differ slightly from those reported in Figure 2 as these are calculated only on Ce core-I glycans examined through exhaustive MSn and not the total O-glycan pool as seen in Figure 2.
b
Figures present in parentheses represent 1SD.
c
Figures in parentheses represent 1SD expressed in %.