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. 2014 Oct 8;9(10):e108859. doi: 10.1371/journal.pone.0108859

Figure 4. SERPINA3K (SA3K) downregulated Wnt signaling pathway.

Figure 4

(A) Representative images of Western blot with anti-β-catenin and anti-LRP6 antibodies in the PECs after treatment of SA3K at concentration of 0, 80, 160, and 320 nM for 24 hours. (B) Statistic analysis of the western blot data of β-catenin. Data were presented as mean±SEM; n = 4; **: p<0.01. (C) Statistic analysis of the Western blot data of LRP6. Data were presented as mean±SEM; n = 5; *: p<0.05. (D) Representative images of Western blot with anti-nonphospho-β-catenin antibody in the PECs after treatment of SA3K at concentration of 0, 80, 160 and 320 nM for 24 hours. (E) Statistic analysis of the Western blot data of nonphospho-β-catenin. Data were presented as mean±SEM; n = 3; *: p<0.05, **: p<0.01.