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. Author manuscript; available in PMC: 2014 Oct 8.
Published in final edited form as: Ann Intern Med. 2014 Feb 4;160(3):171. doi: 10.7326/M13-1484

Appendix Table 1. Search Strategy.

MEDLINE (Ovid) Search Strategy
1 fecal.ti,ab,hw. (38014)
2 faecal.ti,ab,hw. (16604)
3 feces.ti,ab,hw. (73832)
4 1 or 2 or 3 (102056)
5 exp immunoassay/ (403733)
6 exp enzyme-linked immunosorbent assay/ (115110)
7 immunochemi$.ti,ab,hw. (26200)
8 exp Immunochemistry/ (238397)
9 or/5-8 (617537)
10 4 and 9 (4973)
11 FIT.ti,ab,hw. (66545)
12 guaiac.ti,ab,hw. (637)
13 occult blood.ti,ab,hw. (5627)
14 fobt$.ti,ab. (840)
15 fob$.ti,ab. (1502)
16 ifobt.ti,ab. (55)
17 ifob$.ti,ab,hw. (58)
18 or/7,10-17 (103072)
19 Insure.mp. (2487)
20 Inform.mp. (25162)
21 19 or 20 (27634)
22 18 and 21 (317)
23 Instant-view.mp. (5)
24 Instant View.mp. (5)
25 Hemoccult.mp. (520)
26 Immocare.mp. (3)
27 Flexsure.mp. (28)
28 Monohaem.mp. (33)
29 Hemosure.mp. (1)
30 Occultech.mp. (1)
31 Quickvue.mp. (89)
32 Clearview.mp. (86)
33 Hemoquant.mp. (47)
34 Hema screen.mp. (2)
35 Hema-screen.mp. (2)
36 Innovacon.mp. (1)
37 OC-Micro.mp. (9)
38 OC Micro.mp. (9)
39 OC-Sensor.mp. (17)
40 OC Sensor.mp. (17)
41 OC-Hemodia.mp. (16)
42 OC Hemodia.mp. (16)
43 OC-Light.mp. (2)
44 OC Light.mp. (2)
45 Aimstep.mp. (0)
46 Magstream.mp. (10)
47 Immudia.mp. (6)
48 or/18,22-47 (103377)
49 exp “predictive value of tests”/ (125700)
50 exp “Sensitivity and specificity”/ (371895)
51 exp False Negative Reactions/ (15236)
52 exp False Positive Reactions/ (23021)
53 exp Reproducibility of Results/ (242180)
54 exp Reference Values/ (138214)
55 exp Diagnostic Errors/ (87977)
56 exp Reference Standards/ (31448)
57 exp Observer Variation/ (28598)
58 exp Quality Assurance, Health Care/ (236607)
59 standards.fs. (508061)
60 sensitiv$.ti,ab. (882592)
61 specificit$.ti,ab. (312517)
62 predictive value.ti,ab. (50699)
63 accurac$.ti,ab. (200813)
64 false positive$.ti,ab. (39039)
65 false negative$.ti,ab. (22776)
66 miss rate$.ti,ab. (203)
67 error rate$.ti,ab. (7478)
68 detection rate$.ti,ab. (11682)
69 diagnostic yield$.ti,ab. (4734)
70 likelihood ratio$.ti,ab. (7576)
71 odds ratio/and di.fs. (7310)
72 diagnostic odds ratio$.ti,ab. (443)
73 or/49-72 (2331963)
74 48 and 73 (23874)
75 exp Colorectal Neoplasms/ (134899)
76 exp Colonic Neoplasms/ (63388)
77 exp Sigmoid Neoplasms/ (3740)
78 exp Rectal Neoplasms/ (35360)
79 exp Intestinal Polyps/ (11351)
80 exp Colonic Polyps/ (5666)
81 colon cancer.ti,ab,hw. (26207)
82 colonic cancer.ti,ab,hw. (2114)
83 colorectal cancer.ti,ab,hw. (48264)
84 colon neoplasm.ti,ab,hw. (35)
85 colonic neoplasm.ti,ab,hw. (130)
86 colorectal neoplasm.ti,ab,hw. (220)
87 adenoma$.ti,ab,hw. (86623)
88 colon polyp.ti,ab,hw. (157)
89 colonic polyp.ti,ab,hw. (238)
90 colorectal polyp.ti,ab,hw. (181)
91 or/75-90 (223731)
92 74 and 91 (1814)
93 limit 92 to english language (1593)
94 limit 93 to humans (1532)
95 limit 94 to yr=”2008 - 2012” (447)
DARE, Cochrane Database, and HTA Search Strategy
#1 occult blood:kw
#2 “fecal occult blood”:ti,ab
#3 “faecal occult blood”:ti,ab
#4 “fecal immunochemical”:ti,ab
#5 “faecal immunochemical”:ti,ab
#6 fobt*:ti,ab
#7 ifobt*:ti,ab
#8 “instant-view”:ti,ab,kw
#9 “instant view”:ti,ab,kw
#10 “Hemoccult':ti,ab,kw
#11 “immocare”:ti,ab,kw
#12 “flexsure obt”:ti,ab,kw
#13 “monohaem”:ti,ab,kw
#14 “hemosure”:ti,ab,kw
#15 “hemoccult ict':ti,ab,kw
#16 “Occultech”:ti,ab,kw
#17 “Quickvue”:ti,ab,kw
#18 “clearview”:ti,ab,kw
#19 “hemoquant':ti,ab,kw
#20 “hema screen”:ti,ab,kw
#21 “hemascreen”:ti,ab,kw
#22 “hema-screen”:ti,ab,kw
#23 “innovacon”:ti,ab,kw
#24 “oc micro”:ti,ab,kw
#25 “oc-micro”:ti,ab,kw
#26 “oc sensor”:ti,ab,kw
#27 “oc-sensor”:ti,ab,kw
#28 “oc light”:ti,ab,kw
#29 “oc-light”:ti,ab,kw
#30 “oc hemodia”:ti,ab,kw
#31 “oc-hemodia”:ti,ab,kw
#32 “aimstep”:ti,ab,kw
#33 “magstream”:ti,ab,kw
#34 “immudia”:ti,ab,kw
#35 #1 or #2 or #3 or #4 or #5 or #6 or #7 or #8 or #9 or #10 or #11 or #12 or #13 or #14 or #15 or #16 or #17 or #18 or #19 or #20 or #21 or #22 or #23 or #24 or #25 or #26 or #27 or #28 or #29 or #30 or #31 or #32 or #33 or #34
#36 “sensitivity”:kw
#37 “specificity”:kw
#38 “predictive value”:kw
#39 “roc”:kw
#40 receiver next operat*:kw
#41 false next negative:kw
#42 false next positive:kw
#43 diagnostic next error*:kw
#44 reproducibility:kw
#45 reference next value*:kw
#46 refererence next standards:kw
#47 diagnostic next accuracy:kw
#48 diagnostic next value:kw
#49 #36 or #37 or #38 or #39 or #40 or #41 or #42 or #43 or #44 or #45 or #46 or #47 or #48
#50 #35 and #49
#51 sensitiv*.ti,ab
#52 specificit*:ti,ab
#53 predictive next value:ti,ab
#54 accurac*:ti,ab
#55 miss next rate*:ti,ab
#56 detection next rate*:ti,ab
#57 diagnostic next yield*:ti,ab
#58 likelihood next ratio*.ti,ab
#59 diagnostic next odds next ratio*.ti,ab
#60 “odds ratio” and “diagnosis”:kw
#61 #52 or #53 or #54 or #55 or #56 or #57 or #58 or #59 or #60
#62 #35 and #61
#63 #50 or #62
#64 screening:kw
#65 screen*:ti,ab
#66 #64 or #65
#67 #63 and #66 from 2008 to 2012
EMBASE Search Strategy
#1 Fecal
#2 faecal
#3 feces
#4 #1 OR #2 OR #3
#5 ‘immunochemistry’/exp
#6 immunochem*
#7 #5 OR #6
#8 #4 AND #7
#9 fit:ab,ti
#10 guaiac:ab,ti
#11 ‘occult blood’
#12 fobt*
#13 fob*
#14 ifobt
#15 ifob*
#16 #6 OR #8 OR #9 OR #10 OR #11 OR #12 OR #13 OR #14 OR #15
#17 insure
#18 inform
#19 #17 OR #18
#20 #16 AND #19
#21 ‘instant view’
#22 hemoccult
#23 immocare
#24 flexsure
#25 monohaem
#26 hemosure
#27 occultech
#28 quickvue
#29 clearview
#30 hemoquant
#31 ‘hema screen’
#32 innovacon
#33 ‘oc micro’
#34 ‘oc sensor’
#35 ‘oc hemodia’
#36 ‘oc light’
#37 aimstep
#38 magstream
#39 immudia
#40 #16 OR #20 OR #21 OR #22 OR #23 OR #24 OR #25 OR #26 OR #27 OR #28 OR #29 OR #30 OR #31 OR #32 OR #33 OR #34 OR #35 OR #36 OR #37 OR #38 OR #39
#41 ‘predictive value’/de
#42 ‘sensitivity and specificity’/de
#43 ‘laboratory diagnosis’/exp
#44 ‘reproducibility’/de
#45 ‘reference value’/de
#46 ‘diagnostic error’/exp
#47 ‘diagnostic test accuracy study’/de
#48 ‘diagnostic accuracy’/de
#49 ‘diagnostic value’/de
#50 ‘standard’/de
#51 ‘gold standard’/de
#52 ‘observer variation’/de
#53 ‘health care quality’/de
#54 ‘biomedical technology assessment’/de
#55 ‘clinical effectiveness’/de
#56 ‘clinical indicator’/de
#57 ‘medical error’/exp
#58 ‘root cause analysis’/de
#59 ‘good laboratory practice’/de
#60 ‘validation process’/de
#61 sensitiv*:ab,ti
#62 specificit*:ab,ti
#63 ‘predictive value’:ab,ti
#64 accurac*:ab,ti
#65 (false NEXT/1 positive*):ab,ti
#66 (false NEXT/1 negative*):ab,ti
#67 (miss NEXT/1 rate*):ab,ti
#68 (error NEXT/1 rate*):ab,ti
#69 (detection NEXT/1 rate*):ab,ti
#70 (diagnostic NEXT/1 yield*):ab,ti
#71 (likelihood NEXT/1 ratio*):ab,ti
#72 ‘odds ratio’:ab,ti AND diagnosis:ab,ti
#73 risk:ab,ti AND diagnosis:ab,ti
#74 ‘diagnostic odds ratio’:ab,ti OR‘diagnostic odds ratios’:ab,ti
#75 ‘diagnostic accuracy’
#76 ‘reference standard’:ab,ti OR ‘reference standards’:ab,ti
#77 #41 OR #42 OR #43 OR #44 OR #45 OR #46 OR #47 OR #48 OR #49 OR #50 OR #51 OR #52 OR #53 OR #54 OR #55 OR #56 OR #57 OR #58 OR #59 OR #60 OR #61 OR #62 OR #63 OR #64 OR #65 OR #66 OR #67 OR #68 OR #69 OR #70 OR #71 OR #72 OR #73 OR #74 OR #75 OR #76
#78 #40 AND #77
#79 ‘colon tumor’/exp
#80 ‘rectum tumor’/exp
#81 ‘intestine polyp’/exp
#82 ‘colon polyp’/exp
#83 ‘colon cancer’:ab,ti
#84 ‘colonic cancer’:ab,ti
#85 ‘colorectal cancer’:ab,ti
#86 ‘colon neoplasm’:ab,ti
#87 ‘colonic neoplasm’:ab,ti
#88 ‘colorectal neoplasm’:ab,ti
#89 adenoma*:ab,ti
#90 ‘colon polyp’:ab,ti
#91 ‘colonic polyp’:ab,ti
#92 ‘colorectal polyp’:ab,ti
#93 #79 OR #80 OR #81 OR #82 OR #83 OR #84 OR #85 OR #86 OR #87 OR #88 OR #89 OR #90 OR #91 OR #92
#94 #78 AND #93
#95 #78 AND #93 AND [english]/lim
#96 #78 AND #93 AND [english]/lim NOT ([animals]/lim NOT ([humans]/lim OR ‘patient’/exp))
#97 #78 AND #93 AND [english]/lim NOT ([animals]/lim NOT ([humans]/lim OR ‘patient’/exp)) NOT ‘conference abstract’/it
#98 #78 AND #93 AND [english]/lim NOT ([animals]/lim NOT ([humans]/lim OR ‘patient’/exp)) NOT ‘conference abstract’/it AND [2008-2012]/py