Appendix Table 3. Results of Bivariate Meta-regression With Covariates.
| Category | Studies, n | Sensitivity (95% CI) | P Value | Specificity (95% CI) | P Value |
|---|---|---|---|---|---|
| Geographic region | |||||
|
| |||||
| Asian countries | 10 | 0.75 (0.63–0.87) | 0.04 | 0.94 (0.92–0.96) | <0.01 |
|
| |||||
| Non-Asian countries | 9 | 0.83 (0.72–0.94) | 0.04 | 0.94 (0.92–0.96) | <0.01 |
| FIT format | |||||
|
| |||||
| Quantitative | 11 | 0.73 (0.61–0.85) | 0.01 | 0.94 (0.92–0.96) | <0.01 |
|
| |||||
| Qualitative | 8 | 0.85 (0.75–0.95) | 0.01 | 0.94 (0.91–0.96) | <0.01 |
| Patient age | |||||
|
| |||||
| <40 y | 4 | 0.74 (0.55–0.94) | 0.24 | 0.94 (0.91–0.97) | <0.01 |
|
| |||||
| ≥40 y | 14 | 0.79 (0.70–0.89) | 0.24 | 0.94 (0.93–0.96) | <0.01 |
FIT = fecal immunochemical test.